Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28728490 | 0.82 | ATM (0.62) | MAPTATMSMN1; SMN2GAAPOLB | |
| SCHEMBL5463743 | 0.77 | MAPT (0.77) | LMNAMAPTATMSMN1; SMN2GAA | |
| SCHEMBL10769241 | 0.73 | LMNA (0.70) | LMNAMAPTATMSMN1; SMN2GAA | |
| SCHEMBL5524600 | 0.70 | LMNA (0.62) | LMNAMAPTATMSMN1; SMN2GAA | |
| SCHEMBL9260915 | 0.70 | SMN1; SMN2 (0.48) | LMNAMAPTATMSMN1; SMN2GAA | |
| SCHEMBL11055736 | 0.69 | ALDH1A1 (0.56) | LMNAMAPTGAAKMT2APOLB | |
| SCHEMBL5532869 | 0.69 | POLB (0.73) | LMNAMAPTSMN1; SMN2GAAMEN1 | |
| SCHEMBL11617546 | 0.68 | AGER (0.57) | LMNAMAPTSMN1; SMN2GAAMEN1 | |
| SCHEMBL28812462 | 0.68 | ALDH1A1 (0.48) | LMNAMAPTATMSMN1; SMN2GAA | |
| SCHEMBL10595718 | 0.67 | ATM (0.71) | MAPTATMSMN1; SMN2MAPK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103501769-A | Star polymer nanoshells and methods of preparation thereof | IBM | 2014-01-08 | — | — | CN | disclosed |