Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 10/20 | 0.78 |
| ▸ | DBF4 | Q9UBU7 | 10/20 | 0.78 |
| ▸ | TRPM8 | Q7Z2W7 | 5/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | RARA | P10276 | 1/20 | 0.56 |
| ▸ | RARB | P10826 | 1/20 | 0.56 |
| ▸ | RARG | P13631 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15049258 | 0.89 | CDC7 (0.78) | CDC7DBF4TRPM8ALDH1A1HSD17B10 | |
| SCHEMBL27997093 | 0.86 | CDC7 (0.74) | CDC7DBF4TRPM8KDM4EMAPT | |
| SCHEMBL17318008 | 0.86 | CDC7 (0.73) | CDC7DBF4TRPM8ALDH1A1HSD17B10 | |
| SCHEMBL1316281 | 0.86 | CDC7 (0.77) | CDC7DBF4TRPM8ALDH1A1HSD17B10 | |
| Hydrochloric Acid SCHEMBL15049014 | 0.85 | CDC7 (0.73) | CDC7DBF4TRPM8ALDH1A1KDM4E | |
| SCHEMBL6338322 | 0.84 | TRPM8 (1.00) | CDC7DBF4TRPM8KDM4EMAPT | |
| SCHEMBL4503056 | 0.84 | CDC7 (0.88) | CDC7DBF4TRPM8ALDH1A1HSD17B10 | |
| SCHEMBL1726531 | 0.84 | TRPM8 (0.71) | CDC7DBF4TRPM8ALDH1A1HSD17B10 | |
| SCHEMBL23702797 | 0.83 | CDC7 (0.73) | CDC7DBF4TRPM8ALDH1A1HSD17B10 | |
| SCHEMBL289229 | 0.83 | CDC7 (0.73) | CDC7DBF4TRPM8ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101959882-B | Imidazole carbonyl compound | DAIICHI SANKYO CO LTD | 2013-09-11 | — | — | CN | disclosed |