Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 6/20 | 0.73 |
| ▸ | DBF4 | Q9UBU7 | 6/20 | 0.73 |
| ▸ | TRPM8 | Q7Z2W7 | 5/20 | 0.73 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 3/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | RARA | P10276 | 1/20 | 0.60 |
| ▸ | RARB | P10826 | 1/20 | 0.60 |
| ▸ | RARG | P13631 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1316281 | 0.97 | CDC7 (0.77) | CDC7DBF4TRPM8LMNASMN1; SMN2 | |
| SCHEMBL290013 | 0.91 | CDC7 (0.68) | CDC7DBF4TRPM8LMNASMN1; SMN2 | |
| SCHEMBL2880861 | 0.90 | CDC7 (0.67) | CDC7DBF4TRPM8LMNASMN1; SMN2 | |
| SCHEMBL8867673 | 0.90 | CDC7 (0.67) | CDC7DBF4TRPM8LMNASMN1; SMN2 | |
| SCHEMBL892889 | 0.89 | CDC7 (0.77) | CDC7DBF4TRPM8LMNASMN1; SMN2 | |
| SCHEMBL289996 | 0.89 | CDC7 (0.65) | CDC7DBF4TRPM8LMNASMN1; SMN2 | |
| SCHEMBL8867028 | 0.88 | CDC7 (0.71) | CDC7DBF4TRPM8LMNASMN1; SMN2 | |
| SCHEMBL290384 | 0.87 | CDC7 (0.75) | CDC7DBF4TRPM8LMNAALDH1A1 | |
| SCHEMBL2823339 | 0.86 | CDC7 (0.73) | CDC7DBF4TRPM8LMNASMN1; SMN2 | |
| SCHEMBL2885887 | 0.86 | TRPM8 (0.78) | CDC7DBF4TRPM8LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427447-A2 | SMALL MOLECULE INHIBITORS OF INFLUENZA A AND B VIRUS AND RESPIRATORY SYNCYTIAL VIRUS REPLICATION | Pike Pharma GmbH (CH) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010128163-A2 | SMALL MOLECULE INHIBITORS OF INFLUENZA A AND B VIRUS AND RESPIRATORY SYNCYTIAL VIRUS REPLICATION | PIKE PHARMA GMBH (CH) | 2010-11-11 | — | — | WO | disclosed |