Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 20/20 | 0.63 |
| ▸ | ADRB1 | P08588 | 16/20 | 0.61 |
| ▸ | ADRB3 | P13945 | 6/20 | 0.60 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.58 |
| ▸ | DRD2 | P14416 | 2/20 | 0.56 |
| ▸ | DRD1 | P21728 | 2/20 | 0.56 |
| ▸ | DRD4 | P21917 | 2/20 | 0.56 |
| ▸ | DRD3 | P35462 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27950356 | 0.93 | ADRB2 (0.62) | ADRB2ADRB1DRD2DRD1DRD4 | |
| SCHEMBL28807376 | 0.86 | ADRB2 (0.68) | ADRB2ADRB1 | |
| SCHEMBL15777969 | 0.83 | ADRB2 (0.56) | ADRB2ADRB1 | |
| SCHEMBL17074669 | 0.82 | ADRB2 (0.70) | ADRB2ADRB1ADRB3 | |
| SCHEMBL17074668 | 0.82 | ADRB2 (0.70) | ADRB2ADRB1ADRB3 | |
| SCHEMBL16205030 | 0.80 | ADRB2 (0.74) | ADRB2ADRB1 | |
| SCHEMBL16205035 | 0.80 | ADRB2 (0.74) | ADRB2ADRB1 | |
| SCHEMBL16205033 | 0.80 | ADRB2 (0.74) | ADRB2ADRB1 | |
| SCHEMBL16205032 | 0.79 | ADRB2 (0.58) | ADRB2ADRB1ADRB3DRD2DRD1 | |
| SCHEMBL17074689 | 0.79 | ADRB2 (0.74) | ADRB2ADRB1ADRB3CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103562198-A | Compounds having muscarinic receptor antagonist and beta2 adrenergic receptor agonist activity | CHIESI FARMA SPA | 2014-02-05 | — | — | CN | claimed |
| CN-103562198-A | Compounds having muscarinic receptor antagonist and beta2 adrenergic receptor agonist activity | CHIESI FARMA SPA | 2014-02-05 | — | — | CN | disclosed |