Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | AKT2 | P31751 | 1/20 | 0.44 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | SGK1 | O00141 | 1/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27950531 | 0.94 | BACE1 (0.41) | HRH3AKT2CD274TAAR1NOS3 | |
| SCHEMBL3780634 | 0.85 | HRH3 (0.52) | HRH3AKT2CD274TAAR1NOS3 | |
| SCHEMBL22400156 | 0.81 | HRH3 (0.48) | HRH3AKT2CD274TAAR1NOS3 | |
| SCHEMBL21725660 | 0.79 | TAAR1 (0.53) | HRH3AKT2CD274TAAR1LOXL2 | |
| SCHEMBL19503101 | 0.75 | ESR2 (0.44) | AKT2CD274BACE1 | |
| SCHEMBL3785998 | 0.74 | CSNK2A1 (0.58) | AKT2CD274TAAR1HTR7CSNK2A1 | |
| SCHEMBL19636314 | 0.74 | HRH3 (0.74) | HRH3TAAR1ADRB2LOXL2LTA4H | |
| SCHEMBL18676904 | 0.73 | LMNA (0.42) | — | |
| SCHEMBL3789540 | 0.73 | HRH3 (0.52) | HRH3AKT2CD274TAAR1NOS3 | |
| SCHEMBL3793564 | 0.73 | HTR7 (0.56) | HRH3AKT2CD274TAAR1HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103570620-B | The luxuriant and rich with fragrance compounds of a kind of 1,12-imino group benzo [c], intermediate and preparation method and application | 昆山维信诺显示技术有限公司 | 2016-06-15 | — | — | CN | disclosed |
| CN-103570620-A | 1,12-iminobenzo[c]phenanthrene compound, intermediate, preparation method and application of compound | KUNSHAN VISIONOX DISPLAY TECH | 2014-02-12 | — | — | CN | disclosed |