Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.58 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.52 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 2/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | SGK1 | O00141 | 1/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.39 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.39 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.39 |
| ▸ | AKT2 | P31751 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3780634 | 0.88 | HRH3 (0.52) | CSNK2A1TAAR1BACE1HTR7LOXL2 | |
| SCHEMBL3785045 | 0.87 | HTR7 (0.56) | CSNK2A1TAAR1HTR7LOXL2CD274 | |
| SCHEMBL2572842 | 0.85 | CSNK2A1 (0.62) | CSNK2A1TAAR1BACE1HTR7DPP4 | |
| SCHEMBL18934330 | 0.84 | HTR7 (0.47) | CSNK2A1TAAR1HTR7DPP4LOXL2 | |
| SCHEMBL2208511 | 0.82 | ESR2 (0.46) | BACE1MEN1LMNAGAAKMT2A | |
| SCHEMBL27508195 | 0.82 | CSNK2A1 (0.69) | CSNK2A1TAAR1BACE1DPP4LOXL2 | |
| Toluene SCHEMBL28751232 | 0.80 | CSNK2A1 (0.57) | CSNK2A1TAAR1BACE1DPP4LOXL2 | |
| SCHEMBL6547024 | 0.79 | PSMB5 (0.50) | BACE1HTR7MEN1LMNAGAA | |
| SCHEMBL3789650 | 0.78 | CSNK2A1 (0.59) | CSNK2A1TAAR1BACE1DPP4LOXL2 | |
| SCHEMBL3785979 | 0.78 | CSNK2A1 (0.51) | CSNK2A1TAAR1HTR7DPP4LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2010-04-08 | — | — | US | disclosed |
| EP-1914221-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | NISCH, BLVRB, BBOX1 | CSNK2A1 4767/4885TAAR1 1746/4885BACE1 925/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.