Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.58 |
| ▸ | ACHE | P22303 | 1/20 | 0.58 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ACP3 | P15309 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | RGS12 | O14924 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isopropylbenzene SCHEMBL3475008 | 0.97 | LMNA (0.61) | LMNATSHRALOX12ACHEADRA2C | |
| Isopropylbenzene SCHEMBL338185 | 0.97 | LMNA (0.61) | LMNATSHRALOX12ACHEADRA2C | |
| Toluene SCHEMBL29188898 | 0.92 | LMNA (0.61) | LMNATSHRALOX12ACHEKDM4E | |
| P-Cymene SCHEMBL8208471 | 0.90 | ACHE (0.58) | LMNATSHRALOX12ACHEHIF1A | |
| P-Cymene SCHEMBL10942903 | 0.90 | ACHE (0.58) | LMNATSHRALOX12ACHEHIF1A | |
| P-Cymene SCHEMBL1292746 | 0.90 | ACHE (0.50) | LMNATSHRALOX12ACHESMN1; SMN2 | |
| Isopropylbenzene SCHEMBL23421101 | 0.89 | ADRA2C (0.52) | LMNATSHRALOX12ADRA2CKDM4E | |
| Isopropylbenzene SCHEMBL4795494 | 0.89 | ADRA2C (0.52) | LMNATSHRALOX12ADRA2CKDM4E | |
| Isopropylbenzene SCHEMBL16627 | 0.89 | ADRA2C (0.52) | LMNATSHRALOX12ADRA2CKDM4E | |
| Isopropylbenzene SCHEMBL30804544 | 0.89 | ADRA2C (0.52) | LMNATSHRALOX12ADRA2CKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109912569-B | Novel preparation method of esomeprazole magnesium trihydrate and intermediate thereof | 浙江康德药业集团股份有限公司 | 2020-10-27 | — | — | CN | claimed |
| CN-103570686-B | Method for synthesizing and refining esomeprazole sodium | HARBIN PHARMACEUTICAL GROUP TECHNOLOGY CT | 2015-04-01 | — | — | CN | claimed |
| CN-103570686-A | Method for synthesizing and refining esomeprazole sodium | HARBIN PHARMACEUTICAL GROUP TECHNOLOGY CT | 2014-02-12 | — | — | CN | claimed |
| CN-109912569-B | Novel preparation method of esomeprazole magnesium trihydrate and intermediate thereof | 浙江康德药业集团股份有限公司 | 2020-10-27 | — | — | CN | disclosed |
| CN-103936715-B | The process for purification of a kind of Esomeprazole sodium and synthetic method | 哈尔滨珍宝制药有限公司 | 2016-08-24 | — | — | CN | disclosed |
| CN-103570686-B | Method for synthesizing and refining esomeprazole sodium | HARBIN PHARMACEUTICAL GROUP TECHNOLOGY CT | 2015-04-01 | — | — | CN | disclosed |
| CN-103936715-A | Refining method and synthesis method of esomeprazole | HARBIN ZHENBAO PHARMACEUTICAL CO LTD | 2014-07-23 | — | — | CN | disclosed |
| CN-103570686-A | Method for synthesizing and refining esomeprazole sodium | HARBIN PHARMACEUTICAL GROUP TECHNOLOGY CT | 2014-02-12 | — | — | CN | disclosed |