SCHEMBL27936749

SCHEMBL27936749

[CH2]C(Br)(c1ccccc1)[N+](=O)[O-]

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.42
LMNA P02545 1/20 0.42
FBP1 P09467 4/20 0.36
CYP19A1 P11511 1/20 0.35
TSHR P16473 2/20 0.35
KCNN4 O15554 1/20 0.35
TDP1 Q9NUW8 1/20 0.34
L3MBTL1 Q9Y468 2/20 0.33
CYP1A2 P05177 2/20 0.33
MEN1 O00255 1/20 0.33
CRHBP P24387 1/20 0.33
KMT2A Q03164 1/20 0.33
ATM Q13315 1/20 0.33
CRHR2 Q13324 1/20 0.33
TLR9 Q9NR96 1/20 0.33
HPGD P15428 1/20 0.33
ALOX12 P18054 1/20 0.33
NPC1 O15118 1/20 0.32
RECQL P46063 1/20 0.32
RAB9A P51151 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9723894 0.81 ALDH1A1 (0.42) ALDH1A1LMNAFBP1CYP19A1TSHR
SCHEMBL4613619 0.78 ALDH1A1 (0.44) ALDH1A1LMNAFBP1CYP19A1TSHR
SCHEMBL1167741 0.78 ALDH1A1 (0.44) ALDH1A1LMNAFBP1CYP19A1TSHR
SCHEMBL27952347 0.77 CYP1A2 (0.40) ALDH1A1LMNAFBP1CYP19A1TSHR
SCHEMBL4615537 0.76 ALDH1A1 (0.42) ALDH1A1LMNAFBP1CYP19A1TDP1
SCHEMBL28383675 0.75 ALDH1A1 (0.46) ALDH1A1LMNAFBP1CYP19A1TSHR
SCHEMBL1194233 0.75 ALDH1A1 (0.46) ALDH1A1LMNAFBP1CYP19A1TSHR
SCHEMBL114442 0.75 ALDH1A1 (0.46) ALDH1A1LMNAFBP1CYP19A1TSHR
SCHEMBL20942950 0.74 ALDH1A1 (0.44) ALDH1A1LMNAFBP1CYP19A1TSHR
SCHEMBL8932003 0.74 MAPT (0.43) ALDH1A1LMNAFBP1KCNN4KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103570691-B Chiral pyrrolidine functionalized imidazolium salt, and preparation method and application thereof UNIV SHANXI 2015-05-13 CN disclosed
CN-103570691-A Chiral pyrrolidine functionalized imidazolium salt, and preparation method and application thereof UNIV SHANXI 2014-02-12 CN disclosed