Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | FBP1 | P09467 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3037176 | 0.80 | ALDH1A1 (0.44) | ALDH1A1LMNAFBP1TSHRKCNN4 | |
| SCHEMBL1167741 | 0.80 | ALDH1A1 (0.44) | ALDH1A1LMNAFBP1TSHRKCNN4 | |
| SCHEMBL4615537 | 0.78 | ALDH1A1 (0.42) | ALDH1A1LMNAFBP1CYP19A1TDP1 | |
| SCHEMBL27936749 | 0.78 | ALDH1A1 (0.42) | ALDH1A1LMNAFBP1TSHRKCNN4 | |
| SCHEMBL28383675 | 0.77 | ALDH1A1 (0.46) | ALDH1A1LMNAFBP1TSHRKCNN4 | |
| SCHEMBL1194233 | 0.77 | ALDH1A1 (0.46) | ALDH1A1LMNAFBP1TSHRKCNN4 | |
| SCHEMBL114442 | 0.77 | ALDH1A1 (0.46) | ALDH1A1LMNAFBP1TSHRKCNN4 | |
| SCHEMBL20942950 | 0.76 | ALDH1A1 (0.44) | ALDH1A1LMNAFBP1TSHRKCNN4 | |
| SCHEMBL7025394 | 0.76 | ALDH1A1 (0.41) | ALDH1A1LMNAFBP1KCNN4KMT2A | |
| SCHEMBL8932003 | 0.76 | MAPT (0.43) | ALDH1A1LMNAFBP1KCNN4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210005931-A1 | NONAQUEOUS ELECTROLYTE, ENERGY STORAGE DEVICE, AND METHOD FOR PRODUCING ENERGY STORAGE DEVICE | GS YUASA INTERNATIONAL LTD. (JP) | 2021-01-07 | — | — | US | disclosed |
| EP-3477758-B1 | NONAQUEOUS ELECTROLYTE, POWER STORAGE ELEMENT, AND METHOD FOR PRODUCING POWER STORAGE ELEMENT | GS YUASA INT LTD (JP) | 2020-12-16 | — | — | EP | disclosed |
| EP-3477758-A1 | NONAQUEOUS ELECTROLYTE, POWER STORAGE ELEMENT, AND METHOD FOR PRODUCING POWER STORAGE ELEMENT | GS Yuasa International Ltd. (JP) | 2019-05-01 | — | — | EP | disclosed |
| US-7365063-B2 | Quinazolinone and benzoxazinone derivatives and uses thereof | ROCHE PALO ALTO LLC (US) | 2008-04-29 | — | — | US | disclosed |
| EP-1708713-B1 | 1-BENZYL-5-PIPERAZIN-1-YL-3,4 DIHYDRO-1H-QUINAZOLIN-2-ONE DERIVATIVES AND THE RESPECTIVE 1H-BENZO(1,2,6)THIADIAZINE-2,2-DIOXIDE AND 1,4-DIHYDRO-BENZO(D)(1,3)OXAZIN-2-ONE DERIVATIVES AS MODULATORS OF THE 5-HYDROXYTRYPTAMINE RECEPTOR (5-HT) FOR THE TREATMENT OF DISEASES OF THE CENTRAL NERVOUS SYSTEM | HOFFMANN LA ROCHE (CH) | 2008-03-12 | — | — | EP | disclosed |
| US-20070149510-A1 | Quinazolinone and benzoxazinone derivatives and uses thereof | ROCHE PALO ALTO LLC | 2007-06-28 | — | — | US | disclosed |
| US-7196087-B2 | Quinazolinone and benzoxazinone derivatives and uses thereof | ROCHE PALO ALTO LLC (US) | 2007-03-27 | — | — | US | disclosed |
| EP-1708713-A1 | 1-BENZYL-5-PIPERAZIN-1-YL-3,4 DIHYDRO-1H-QUINAZOLIN-2-ONE DERIVATIVES AND THE RESPECTIVE 1H-BENZO(1,2,6)THIADIAZINE-2,2-DIOXIDE AND 1,4-DIHYDRO-BENZO(D)(1,3)OXAZIN-2-ONE DERIVATIVES AS MODULATORS OF THE 5-HYDROXYTRYPTAMINE RECEPTOR (5-HT) FOR THE TREATMENT OF DISEASES OF THE CENTRAL NERVOUS SYSTEM | F. Hoffman-la Roche AG (CH) | 2006-10-11 | — | — | EP | disclosed |
| WO-2005067933-A1 | 1-BENZYL-5-PIPERAZIN-1-YL-3,4 DIHYDRO-1H-QUINAZOLIN-2-ONE DERIVATIVES AND THE RESPECTIVE 1H-BENZO(1,2,6)THIADIAZINE-2,2-DIOXIDE AND 1,4-DIHYDRO-BENZO(D) (1,3)OXAZIN-2-ONE DERIVATIVES AS MODULATORS OF THE 5-HYDROXYTRYPTAMINE RECEPTOR (5-HT) FOR THE TREATMENT OF DISEASES OF THE CENTRAL NERVOUS SYSTEM | F. HOFFMANN-LA ROCHE AG (CH) | 2005-07-28 | — | — | WO | disclosed |
| US-20050165001-A1 | Quinazolinone and benzoxazinone derivatives and uses thereof | ROCHE PALO ALTO LLC | 2005-07-28 | — | — | US | disclosed |
| CN-1117736-C | Method for producing 2-(3-pyrazolyl-oxymethylene) nitrobenzenes | BASF AG (DE) | 2003-08-13 | — | — | CN | disclosed |
| CN-1105701-C | Method for preparing substituted benzyl bromides | BASF AG (DE) | 2003-04-16 | — | — | CN | disclosed |
| CN-1265639-A | Method for preparing substituted benzyl bromides | BASF AG (DE) | 2000-09-06 | — | — | CN | disclosed |
| CN-1265653-A | Process for preparing 2- (3-pyrazolyl-oxymethylene) nitrobenzene | BASF AG (DE) | 2000-09-06 | — | — | CN | disclosed |
| US-6008307-A | Process for producing olefin polymers using cationic catalysts | EXXON CHEMICAL PATENTS INC (US) | 1999-12-28 | — | — | US | disclosed |
| US-4098831-A | NITROBENZOTRICHLORIDE OR BROMIDE PROCESS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1978-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070149510-A1 | Quinazolinone and benzoxazinone derivatives and uses thereof | NQO2, MLX, CYP4X1 | ALDH1A1 1177/4885LMNA 425/4885FBP1 2022/4885 |
| US-20050165001-A1 | Quinazolinone and benzoxazinone derivatives and uses thereof | NQO2, MLX, CYP4X1 | ALDH1A1 1177/4885LMNA 425/4885FBP1 2022/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.