SCHEMBL27937802

SCHEMBL27937802

CNc1ccc2ccc(F)cc2c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.48
CYP2A6 P11509 1/20 0.48
APP P05067 3/20 0.42
EGFR P00533 2/20 0.39
KDM4E B2RXH2 1/20 0.37
NPC1 O15118 1/20 0.37
CASP3 P42574 1/20 0.37
RAB9A P51151 1/20 0.37
SENP7 Q9BQF6 1/20 0.37
SENP6 Q9GZR1 1/20 0.37
CYP19A1 P11511 1/20 0.37
TNIK Q9UKE5 2/20 0.36
SLC6A4 P31645 2/20 0.36
SLC6A3 Q01959 2/20 0.36
MAPT P10636 2/20 0.36
LMNA P02545 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
LYN P07948 2/20 0.35
BTK Q06187 2/20 0.35
BACE1 P56817 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27919195 0.93 CYP1A2 (0.50) CYP1A2CYP2A6APPEGFRKDM4E
Hydrochloric Acid SCHEMBL6258550 0.91 CYP1A2 (0.48) CYP1A2CYP2A6APPEGFRKDM4E
SCHEMBL25973229 0.86 EGFR (0.47) CYP1A2CYP2A6APPEGFRKDM4E
SCHEMBL8156941 0.78 EGFR (0.48) CYP1A2CYP2A6APPEGFRKDM4E
SCHEMBL29936739 0.78 CYP1A2 (0.72) CYP1A2CYP2A6KDM4ECASP3SENP7
SCHEMBL6564751 0.78 CYP1A2 (0.72) CYP1A2CYP2A6KDM4ECASP3SENP7
SCHEMBL8295486 0.76 CYP2A6 (0.64) CYP1A2CYP2A6APPEGFRKDM4E
SCHEMBL761018 0.75 ALDH1A1 (0.58) CYP1A2CYP2A6KDM4ENPC1CASP3
SCHEMBL29242571 0.74 ALDH1A1 (0.48) CYP2A6EGFRKDM4ESLC6A4SLC6A3
SCHEMBL27937785 0.74 EGFR (0.39) CYP1A2CYP2A6APPEGFRNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103298772-B Method for producing aromatic alcohol or heterocyclic aromatic alcohol MITSUBISHI GAS CHEMICAL CO 2015-06-24 CN disclosed
CN-103298772-A Method for producing aromatic alcohol or heterocyclic aromatic alcohol MITSUBISHI GAS CHEMICAL CO 2013-09-11 CN disclosed