Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.32 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.32 |
| ▸ | CDK9 | P50750 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 2/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17194359 | 0.79 | HSP90B1 (0.33) | HSP90B1CDK9DYRK1ADYRK2 | |
| Hydrochloric Acid SCHEMBL18492665 | 0.78 | HSP90B1 (0.33) | HSP90B1CDK9DYRK1ADYRK2 | |
| SCHEMBL9978109 | 0.78 | SMN1; SMN2 (0.37) | HSP90B1CDK9DYRK1ADYRK2 | |
| SCHEMBL27920622 | 0.77 | ALDH1A1 (0.37) | MTNR1AMTNR1B | |
| SCHEMBL15168288 | 0.70 | GRM2 (0.43) | GRM2 | |
| SCHEMBL16657407 | 0.69 | RAB9A (0.41) | MTNR1AMTNR1B | |
| SCHEMBL27939156 | 0.67 | MAPT (0.35) | — | |
| SCHEMBL15551280 | 0.67 | NUDT1 (0.40) | HSP90B1CDK9DYRK1ADYRK2 | |
| SCHEMBL3669322 | 0.65 | HSP90B1 (0.37) | HSP90B1CDK9DYRK1ADYRK2 | |
| SCHEMBL23100556 | 0.63 | CNR1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103347881-A | Azabenzimidazoles as respiratory syncytial virus antiviral agents | JANSSEN R & D IRELAND | 2013-10-09 | — | — | CN | disclosed |