Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TNF | P01375 | 1/20 | 0.43 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HK1 | P19367 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28813937 | 0.91 | KMT2A (0.53) | MEN1KMT2AKDM4ECYP1A2CYP2C9 | |
| SCHEMBL27939731 | 0.85 | SIGMAR1 (0.46) | MEN1KMT2AMCL1KDM4EHSD17B10 | |
| SCHEMBL27917555 | 0.85 | PTGER4 (0.46) | SMN1; SMN2MEN1KMT2AMAPK1KDM4E | |
| SCHEMBL27979736 | 0.85 | CYP19A1 (0.50) | CYP19A1SMN1; SMN2MEN1KMT2AMAPK1 | |
| SCHEMBL27979701 | 0.84 | CYP19A1 (0.47) | CYP19A1SMN1; SMN2MEN1KMT2AMAPK1 | |
| SCHEMBL27891716 | 0.84 | CYP19A1 (0.56) | CYP19A1SMN1; SMN2MEN1KMT2AMAPK1 | |
| SCHEMBL27979711 | 0.82 | ALDH1A1 (0.45) | SMN1; SMN2MEN1KMT2AKDM4EHSD17B10 | |
| SCHEMBL27979707 | 0.82 | CYP19A1 (0.53) | CYP19A1SMN1; SMN2MEN1KMT2AMAPK1 | |
| SCHEMBL2215283 | 0.81 | CYP19A1 (0.49) | CYP19A1SMN1; SMN2MEN1KMT2AMAPK1 | |
| SCHEMBL28802124 | 0.81 | PTGER4 (0.44) | MEN1KMT2AKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101429198-B | Banisterine derivant and uses thereof | XINJIANG HUASHIDAN MEDICAMENTS RES CO LTD | 2013-10-23 | — | — | CN | disclosed |