Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 6/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27917555 | 0.84 | PTGER4 (0.46) | PTGER4GAAKMT2AMEN1RXFP1 | |
| SCHEMBL27939722 | 0.81 | CYP19A1 (0.50) | GAAKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL27979711 | 0.81 | ALDH1A1 (0.45) | GAAKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL27921223 | 0.80 | PGR (0.47) | ALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL27917602 | 0.79 | ALKBH5 (0.45) | GAAALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL27939731 | 0.77 | SIGMAR1 (0.46) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL28813937 | 0.75 | KMT2A (0.53) | GAAKMT2AMEN1RXFP1ALDH1A1 | |
| SCHEMBL27979690 | 0.75 | MAPT (0.40) | PTGER4KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL146503 | 0.71 | CYP1A2 (0.56) | GAAKMT2AMEN1RXFP1ALDH1A1 | |
| SCHEMBL553110 | 0.68 | ALDH1A1 (0.49) | PTGER4GAAKMT2AMEN1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103070862-A | Application of harmine derivative in preparation of antibacterial drugs | XINJIANG HUASHIDAN PHARMACEUTICAL RES CO LTD | 2013-05-01 | — | — | CN | disclosed |