Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.38 |
| ▸ | CES1 | P23141 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | TGM2 | P21980 | 2/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7895041 | 0.78 | CYP1A2 (0.38) | THRBCYP2C19ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL2794004 | 0.73 | ALDH1A1 (0.40) | CES2CES1THRBCYP2C19TGM2 | |
| SCHEMBL2362357 | 0.71 | CES2 (0.44) | CES2CES1THRBCYP2C19TGM2 | |
| SCHEMBL351499 | 0.71 | THRB (0.45) | CES2CES1THRBCYP2C19TGM2 | |
| SCHEMBL2793999 | 0.69 | THRB (0.39) | CES2CES1THRBCYP2C19TGM2 | |
| SCHEMBL8883023 | 0.69 | MAPK1 (0.53) | CES1THRBCYP2C19TGM2AKT1 | |
| SCHEMBL385457 | 0.69 | THRB (0.53) | THRBCYP2C19TGM2AKT1SRC | |
| SCHEMBL30300800 | 0.69 | THRB (0.53) | THRBCYP2C19TGM2AKT1SRC | |
| SCHEMBL24708816 | 0.67 | THRB (0.43) | CES2CES1THRBCYP2C19TGM2 | |
| SCHEMBL30881617 | 0.67 | THRB (0.43) | CES2CES1THRBCYP2C19TGM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2190652-B1 | PROCESS FOR APPLYING A COATED OR UNCOATED FILM ON A LENS SUBSTRATE | ESSILOR INT (FR) | 2015-10-21 | — | — | EP | disclosed |
| US-8202392-B2 | Process for applying a coated or uncoated film on a lens substrate | ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) | 2012-06-19 | — | — | US | disclosed |
| US-20100163165-A1 | Process for Applying a Coated or Uncoated Film on a Lens Substrate | ESSILOR INTERNATIONAL (COMPAGINE GENERALE D'OPTIQU (FR) | 2010-07-01 | — | — | US | disclosed |