SCHEMBL27940403

SCHEMBL27940403

CNC(=O)C(O)c1ccccc1COc1cc(NC)c(NC)cc1NC

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
FABP4 P15090 2/20 0.38
FABP5 Q01469 2/20 0.38
KMT2A Q03164 3/20 0.37
BRD4 O60885 2/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
MAPT P10636 2/20 0.34
MEN1 O00255 1/20 0.34
ALDH1A1 P00352 2/20 0.33
HTT P42858 1/20 0.33
KDM4E B2RXH2 2/20 0.33
GAA P10253 1/20 0.33
HDAC8 Q9BY41 2/20 0.32
KCNH2 Q12809 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27952264 0.88 FABP4 (0.38) FABP4FABP5KMT2ABRD4L3MBTL1
SCHEMBL28038429 0.86 FABP4 (0.42) FABP4FABP5KMT2ABRD4L3MBTL1
SCHEMBL27952309 0.83 FABP4 (0.38) FABP4FABP5KMT2AL3MBTL1MEN1
SCHEMBL15402835 0.82 MAPT (0.44) FABP4FABP5KMT2AL3MBTL1MAPT
SCHEMBL27940488 0.82 KCNH2 (0.35) FABP4FABP5KMT2AMEN1KCNH2
SCHEMBL15402172 0.81 MAPT (0.43) FABP4FABP5MAPTALDH1A1GAA
SCHEMBL15401423 0.81 LMNA (0.43) FABP4FABP5KMT2AL3MBTL1MEN1
SCHEMBL15402252 0.81 ALDH1A1 (0.47) FABP4FABP5KMT2AMEN1ALDH1A1
SCHEMBL3498225 0.80 SMN1; SMN2 (0.44) KMT2AMAPTMEN1ALDH1A1HTT
SCHEMBL15402116 0.80 MRGPRX4 (0.44) L3MBTL1MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103641731-B The manufacture method of phenylacetyl amine compound SUMITOMO CHEMICAL CO., LTD. (JP) 2015-10-28 CN disclosed
CN-103588657-A Method for producing phenylacetamide compound SUMITOMO CHEMICAL CO 2014-02-19 CN disclosed