Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.58 |
| ▸ | VNN1 | O95497 | 8/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27954005 | 0.79 | ALDH1A1 (0.38) | RXFP1VNN1LMNAMEN1MAPT | |
| SCHEMBL15067149 | 0.77 | RXFP1 (0.52) | RXFP1VNN1LMNANPSR1MEN1 | |
| SCHEMBL15067437 | 0.75 | RXFP1 (0.65) | RXFP1VNN1LMNANPSR1MEN1 | |
| SCHEMBL9418310 | 0.75 | RXFP1 (0.79) | RXFP1LMNANPSR1MEN1MAPT | |
| SCHEMBL51509 | 0.75 | RXFP1 (0.79) | RXFP1LMNANPSR1MEN1MAPT | |
| SCHEMBL4099287 | 0.74 | ALDH1A1 (0.43) | LMNAMAPTRAB9AHPGDALDH1A1 | |
| SCHEMBL9963642 | 0.71 | MAPT (0.68) | RXFP1LMNANPSR1MEN1MAPT | |
| SCHEMBL10426837 | 0.71 | MAPT (0.62) | RXFP1LMNANPSR1MEN1MAPT | |
| SCHEMBL2435333 | 0.71 | KDM4E (0.50) | LMNAMAPTHPGDALDH1A1CA1 | |
| Ethyne SCHEMBL8195983 | 0.71 | RXFP1 (0.73) | RXFP1LMNANPSR1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103702665-A | Compounds for inflammation and immune-related uses | SYNTA PHARMACEUTICALS CORP | 2014-04-02 | — | — | CN | disclosed |