Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 3/20 | 0.47 |
| ▸ | CTSS | P25774 | 3/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 7/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.42 |
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2397629 | 0.82 | CTSL (0.52) | ATMCTSLCTSSCNR2CTSK | |
| SCHEMBL8683812 | 0.76 | CTSK (0.62) | ATMCTSLCTSSCTSKCTSB | |
| SCHEMBL8683808 | 0.76 | CTSK (0.62) | ATMCTSLCTSSCTSKCTSB | |
| SCHEMBL7580108 | 0.76 | CTSK (0.62) | ATMCTSLCTSSCTSKCTSB | |
| SCHEMBL7551174 | 0.76 | CTSK (0.62) | ATMCTSLCTSSCTSKCTSB | |
| SCHEMBL1398980 | 0.72 | CTSK (0.58) | ATMCTSLCTSSCTSKCTSB | |
| SCHEMBL27510729 | 0.72 | CTSK (0.58) | ATMCTSLCTSSCTSKCTSB | |
| SCHEMBL14233289 | 0.72 | TGM2 (0.55) | CTSLCTSSCTSKCTSBMEN1 | |
| SCHEMBL7446374 | 0.72 | TGM2 (0.55) | CTSLCTSSCTSKCTSBMEN1 | |
| SCHEMBL7446370 | 0.72 | TGM2 (0.55) | CTSLCTSSCTSKCTSBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103370309-A | Substituted N-phenethyltriazoloneacetamides and use thereof | BAYER IP GMBH | 2013-10-23 | — | — | CN | disclosed |