Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27296322 | 0.83 | TP53 (0.62) | TP53MAPTNPC1RAB9APTK2B | |
| SCHEMBL18025752 | 0.76 | IDO1 (0.51) | MAPTNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL14939367 | 0.73 | MAPT (1.00) | TP53MAPTNPC1RAB9APTK2B | |
| SCHEMBL27482099 | 0.72 | IDO1 (0.42) | MAPTKDM4EALDH1A1KMT2AIDO1 | |
| SCHEMBL15299912 | 0.71 | IDO1 (0.41) | MAPTNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL29439898 | 0.70 | GAA (0.55) | MAPTALDH1A1IDO1AR | |
| SCHEMBL11981441 | 0.70 | GAA (0.55) | MAPTALDH1A1IDO1AR | |
| SCHEMBL27481346 | 0.70 | ADRA1A (0.43) | ALDH1A1KMT2AADRA2AIDO1GSK3B | |
| SCHEMBL7878716 | 0.70 | KDM4E (0.40) | TP53MAPTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL15299947 | 0.70 | IDO1 (0.40) | MAPTNPC1RAB9AKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103380125-B | Prepare the method for the oxindole that triazinyl replaces | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-11-25 | — | — | CN | disclosed |
| CN-103380125-A | Method for producing triazinyl-substituted oxindoles | BAYER IP GMBH | 2013-10-30 | — | — | CN | disclosed |