Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.47 |
| ▸ | DRD4 | P21917 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 3/20 | 0.43 |
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16902905 | 0.89 | LMNA (0.47) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL27878248 | 0.88 | CA12 (0.48) | NPC1RAB9AFFAR1MAOAMAOB | |
| SCHEMBL16902903 | 0.87 | DRD4 (0.46) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL16902904 | 0.87 | NR5A1 (0.47) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL17465611 | 0.86 | LMNA (0.62) | RAB9ALMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL16902908 | 0.86 | NR5A1 (0.50) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL16902912 | 0.86 | NR5A1 (0.50) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL16902914 | 0.86 | NR5A1 (0.50) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL16902910 | 0.86 | NR5A1 (0.50) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL16902909 | 0.86 | NR5A1 (0.50) | LMNACYP1A2PTGS1SLC6A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102727470-B | Application of fluorene-9-bisphenol and its derivative in preparation of medicine for preventing and treating cancer | UNIV BEIJING | 2014-02-19 | — | — | CN | disclosed |