Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.61 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.61 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.61 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.61 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.61 |
| ▸ | F12 | P00748 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 2/20 | 0.57 |
| ▸ | CA9 | Q16790 | 2/20 | 0.57 |
| ▸ | MAOA | P21397 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | F2 | P00734 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | USP2 | O75604 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | MIF | P14174 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA3 | P07451 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3366496 | 0.86 | POLB (0.71) | MEN1KMT2AGPR35CA12CA9 | |
| SCHEMBL22479063 | 0.85 | PIM1 (0.60) | KMT2AGRIN1GRIN2AGRIN2BGRIN2C | |
| SCHEMBL11484256 | 0.82 | MAOB (0.74) | GRIN1GRIN2AGRIN2BGRIN2CGPR35 | |
| SCHEMBL27951953 | 0.81 | POLB (0.75) | MEN1KMT2AF12CA12CA9 | |
| SCHEMBL28295864 | 0.80 | MIF (0.72) | MEN1KMT2AMAOAPOLBMAOB | |
| SCHEMBL1808756 | 0.78 | MAOA (0.71) | MEN1KMT2AGRIN1GRIN2AGRIN2B | |
| SCHEMBL93300 | 0.77 | MAOB (0.85) | CA12MAOAMAOBCA2CA4 | |
| SCHEMBL569881 | 0.77 | GPR35 (1.00) | KMT2AGRIN1GRIN2AGRIN2BGRIN2C | |
| SCHEMBL3589538 | 0.77 | MAOB (0.84) | MEN1KMT2ACA12CA9MAOA | |
| SCHEMBL2038036 | 0.77 | MAOA (0.72) | MEN1KMT2AGRIN1GRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103626730-B | A kind of preparation method of Coumarin-3-carboxylic ester derivant | 安徽师范大学 | 2016-08-17 | — | — | CN | disclosed |
| CN-103626730-A | Preparation method for coumarin-3-carboxylic ester derivative | UNIV ANHUI NORMAL | 2014-03-12 | — | — | CN | disclosed |