Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.69 |
| ▸ | HTT | P42858 | 3/20 | 0.69 |
| ▸ | USP2 | O75604 | 2/20 | 0.69 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.68 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.68 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.68 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.68 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.68 |
| ▸ | HPGD | P15428 | 3/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.67 |
| ▸ | CA12 | O43570 | 1/20 | 0.67 |
| ▸ | CA2 | P00918 | 1/20 | 0.67 |
| ▸ | CA3 | P07451 | 1/20 | 0.67 |
| ▸ | CA6 | P23280 | 1/20 | 0.67 |
| ▸ | CA5A | P35218 | 1/20 | 0.67 |
| ▸ | CA7 | P43166 | 1/20 | 0.67 |
| ▸ | CA9 | Q16790 | 1/20 | 0.67 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.67 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11484256 | 0.85 | MAOB (0.74) | MAOAALDH1A1HTTUSP2GRIN1 | |
| SCHEMBL29985431 | 0.84 | KDM4E (0.68) | MAOAALDH1A1HPGDKDM4ECA12 | |
| SCHEMBL17903545 | 0.84 | MAOB (0.72) | MAOAALDH1A1HPGDKDM4ECA12 | |
| SCHEMBL18589240 | 0.84 | MAOB (0.70) | MAOAALDH1A1HPGDKDM4ECA12 | |
| SCHEMBL980429 | 0.83 | MAOA (1.00) | MAOAALDH1A1HTTUSP2GRIN1 | |
| SCHEMBL1367996 | 0.83 | GRIN1 (0.79) | MAOAALDH1A1HTTUSP2GRIN1 | |
| SCHEMBL1367953 | 0.83 | GRIN1 (0.79) | MAOAALDH1A1HTTUSP2GRIN1 | |
| SCHEMBL22502678 | 0.82 | MEN1 (0.72) | MAOAALDH1A1GPR35HPGDKDM4E | |
| SCHEMBL6835643 | 0.82 | KDM4E (0.76) | ALDH1A1HPGDKDM4ECA12CA2 | |
| SCHEMBL10651297 | 0.82 | KDM4E (0.67) | MAOAALDH1A1HPGDKDM4ECA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103626730-B | A kind of preparation method of Coumarin-3-carboxylic ester derivant | 安徽师范大学 | 2016-08-17 | — | — | CN | disclosed |
| CN-103626730-A | Preparation method for coumarin-3-carboxylic ester derivative | UNIV ANHUI NORMAL | 2014-03-12 | — | — | CN | disclosed |
| EP-1801108-B9 | MORPHOLINE COMPOUNDS FOR THE TREATMENT OF INFLAMMATIONS | MITSUBISHI TANABE PHARMA CORP (JP) | 2013-11-20 | — | — | EP | disclosed |
| EP-1801108-B1 | MORPHOLINE COMPOUNDS FOR THE TREATMENT OF INFLAMMATIONS | MITSUBISHI TANABE PHARMA CORP (JP) | 2012-11-14 | — | — | EP | disclosed |
| CN-101014580-B | Morpholine compound | MITSUBISHI PHARMA CORP | 2011-05-04 | — | — | CN | disclosed |
| US-7935700-B2 | Morpholine compound | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2011-05-03 | — | — | US | disclosed |
| US-20070265257-A1 | Morpholine Compound | MITSUBISHI PHARMA CORPORATION (JP) | 2007-11-15 | — | — | US | disclosed |
| CN-101014580-A | Morpholine compound | MITSUBISHI PHARMA CORP (JP) | 2007-08-08 | — | — | CN | disclosed |
| EP-1801108-A1 | MORPHOLINE COMPOUND | Mitsubishi Pharma Corporation (JP) | 2007-06-27 | — | — | EP | disclosed |
| WO-2000021941-A1 | BIOMIMETIC CHELATING AGENTS AND METHODS | SYNCHEM RESERACH, INC. (CA) | 2000-04-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070265257-A1 | Morpholine Compound | CCR3, CCR1, CCR4 | MAOA 3792/4885ALDH1A1 2661/4885HTT 2964/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.