SCHEMBL27952153

SCHEMBL27952153

CCCO[Si](CCCC(N)=O)(OCCC)OCCC

nearest known ligand 0.37

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SOAT1 P35610 2/20 0.37
MEN1 O00255 1/20 0.37
FAAH O00519 1/20 0.37
TP53 P04637 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2C19 P33261 1/20 0.37
KMT2A Q03164 1/20 0.37
CNR1 P21554 1/20 0.35
KDM4E B2RXH2 2/20 0.34
DGKA P23743 1/20 0.31
ACHE P22303 1/20 0.31
ALDH1A1 P00352 1/20 0.30
CES2 O00748 1/20 0.30
CES1 P23141 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27600588 0.91 SOAT1 (0.34) SOAT1MEN1FAAHTP53CYP1A2
SCHEMBL7936281 0.83 ALOX15 (0.36) SOAT1MEN1FAAHTP53CYP1A2
SCHEMBL27940108 0.82 SOAT1 (0.36) SOAT1MEN1FAAHTP53CYP1A2
SCHEMBL28230892 0.82 SOAT1 (0.37) SOAT1MEN1FAAHTP53CYP1A2
Hydrochloric Acid SCHEMBL28983309 0.82 ALOX15 (0.34) SOAT1MEN1FAAHTP53CYP1A2
SCHEMBL1142965 0.79 ACHE (0.39) ACHE
SCHEMBL28011929 0.79 ACHE (0.34) KDM4EACHE
SCHEMBL28380456 0.78 TSHR (0.38) FAAHALDH1A1
SCHEMBL1143006 0.78 ACHE (0.38) MEN1KMT2AACHE
SCHEMBL27988438 0.78 SOAT1 (0.33) SOAT1MEN1FAAHTP53CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103608428-B The optical module of photochromic composition and use said composition 德山株式会社 2016-07-06 CN disclosed
CN-103608428-A Photochromic composition and optical article using same TOKUYAMA CORP 2014-02-26 CN disclosed