Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.32 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27940136 | 0.83 | KDM4E (0.37) | TSHR | |
| SCHEMBL28775470 | 0.73 | GUCY1A1 (0.36) | TTRCYP1A2CYP2C8CHRM1CYP2C9 | |
| SCHEMBL891297 | 0.73 | CA1 (0.39) | TDP1HPGD | |
| SCHEMBL4948565 | 0.70 | HTT (0.40) | TSHRSMN1; SMN2TDP1HPGD | |
| SCHEMBL27767913 | 0.68 | ALDH1A1 (0.37) | TTRCYP1A2CYP2C8CHRM1CYP2C9 | |
| SCHEMBL1081857 | 0.67 | AAK1 (0.31) | SMN1; SMN2TDP1 | |
| SCHEMBL27673016 | 0.67 | ALDH1A1 (0.41) | CYP2C9 | |
| SCHEMBL17102731 | 0.66 | SMN1; SMN2 (0.39) | CYP2C9TSHRSMN1; SMN2TDP1 | |
| SCHEMBL28745434 | 0.65 | CHRM2 (0.51) | SMN1; SMN2 | |
| SCHEMBL28212417 | 0.64 | LMNA (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101420942-B | Small-molecule modulators of TRP-P8 activity | DENDREON CORP | 2014-03-12 | — | — | CN | disclosed |