Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.48 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | CTSG | P08311 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11192262 | 0.97 | ALDH1A1 (0.45) | DPP7ELANECTSGALDH1A1OPRM1 | |
| SCHEMBL13102890 | 0.93 | RAB9A (0.42) | DPP7ELANECTSGALDH1A1OPRM1 | |
| SCHEMBL27797167 | 0.86 | ALDH1A1 (0.45) | ELANECTSGALDH1A1OPRM1OPRK1 | |
| SCHEMBL17001672 | 0.85 | RAB9A (0.39) | ELANECTSGALDH1A1OPRM1OPRK1 | |
| SCHEMBL30477417 | 0.82 | DPP7 (0.46) | DPP7OPRM1OPRK1POLBSMN1; SMN2 | |
| SCHEMBL23343880 | 0.79 | DPP7 (0.50) | DPP7OPRM1OPRK1KMT2APOLB | |
| SCHEMBL18477510 | 0.78 | NR1H2 (0.46) | DPP7OPRK1NPC1 | |
| SCHEMBL30915775 | 0.78 | NR1H2 (0.46) | DPP7OPRK1NPC1 | |
| SCHEMBL30915772 | 0.78 | NR1H2 (0.46) | DPP7OPRK1NPC1 | |
| SCHEMBL30477418 | 0.77 | SMN1; SMN2 (0.53) | ELANECTSGSMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103664739-A | Telaprevir intermediate preparation method | HUNAN KEYUAN BIO PRODUCTS CO LTD | 2014-03-26 | — | — | CN | disclosed |