Methacrylic Acid

Methacrylic Acid

SCHEMBL27952941

C=C(C)C(=O)O.C[SiH](C)CCc1ccccc1

nearest known ligand 0.48

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.48
KEAP1 Q14145 1/20 0.42
SMN1; SMN2 Q16637 2/20 0.40
HDAC2 Q92769 2/20 0.40
HDAC8 Q9BY41 2/20 0.40
HDAC6 Q9UBN7 2/20 0.40
HDAC3 O15379 1/20 0.40
MAPK1 P28482 1/20 0.40
ADRA1A P35348 1/20 0.40
HDAC4 P56524 1/20 0.40
SLC6A3 Q01959 1/20 0.40
HDAC1 Q13547 1/20 0.40
HDAC7 Q8WUI4 1/20 0.40
HDAC10 Q969S8 1/20 0.40
HDAC11 Q96DB2 1/20 0.40
HDAC9 Q9UKV0 1/20 0.40
HDAC5 Q9UQL6 1/20 0.40
FFAR1 O14842 1/20 0.40
HPGD P15428 1/20 0.39
MAOA P21397 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL4656023 0.85 ALDH1A1 (0.59) ALDH1A1KEAP1SMN1; SMN2HDAC2HDAC8
Methacrylic Acid SCHEMBL31554944 0.83 ALDH1A1 (0.57) ALDH1A1KEAP1SMN1; SMN2HDAC2HDAC8
SCHEMBL476138 0.82 TP53 (0.50) ALDH1A1SMN1; SMN2HPGDMAOAMAOB
Phenylethyl Alcohol SCHEMBL27472539 0.79 TDP1 (0.64) ALDH1A1KEAP1SMN1; SMN2HDAC2HDAC8
Ethylbenzene SCHEMBL27804631 0.79 TP53 (0.61) ALDH1A1SMN1; SMN2KDM4ELMNAKMT2A
Butylbenzyl SCHEMBL28147500 0.76 ALDH1A1 (0.55) ALDH1A1SMN1; SMN2HDAC2HDAC8HDAC6
Methacrylic Acid SCHEMBL1082311 0.76 ALDH1A1 (0.60) ALDH1A1KEAP1SMN1; SMN2HDAC2HDAC8
Methacrylic Acid SCHEMBL31051021 0.75 ALDH1A1 (0.48) ALDH1A1KEAP1SMN1; SMN2HDAC2HDAC8
Butylbenzyl SCHEMBL28211360 0.75 ALDH1A1 (0.53) ALDH1A1SMN1; SMN2HDAC2HDAC8HDAC6
Methacrylic Acid SCHEMBL11310406 0.75 THRA (0.61) ALDH1A1HPGDMAPTRXFP1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103658097-A Cleaning process JOTUN AS 2014-03-26 CN disclosed