SCHEMBL476138

SCHEMBL476138

C[SiH](C)CCc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.50
ALDH1A1 P00352 2/20 0.48
HPGD P15428 1/20 0.48
ALOX15 P16050 1/20 0.48
ALOX12 P18054 1/20 0.48
CASP1 P29466 1/20 0.48
HSD17B10 Q99714 1/20 0.48
TAAR1 Q96RJ0 3/20 0.46
ATM Q13315 1/20 0.46
TDP1 Q9NUW8 2/20 0.46
CYP2A6 P11509 1/20 0.46
HTR2A P28223 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
LOXL2 Q9Y4K0 1/20 0.46
AOC3 Q16853 1/20 0.43
MAOA P21397 1/20 0.42
MAOB P27338 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.41
KCNH2 Q12809 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL476048 0.85 L3MBTL1 (0.48) TP53HTR2AAOC3MAOAMAOB
SCHEMBL7749434 0.84 ALDH1A1 (0.48) TP53ALDH1A1HPGDALOX15ALOX12
SCHEMBL2803699 0.83 MAOA (0.52) MAOAMAOBL3MBTL1
Methacrylic Acid SCHEMBL27952941 0.82 ALDH1A1 (0.48) ALDH1A1HPGDTDP1SMN1; SMN2MAOA
SCHEMBL28564556 0.81 SIGMAR1 (0.53) MAOAMAOBL3MBTL1
SCHEMBL31154202 0.81 SIGMAR1 (0.53) MAOAMAOBL3MBTL1
SCHEMBL3481488 0.80 ALDH1A1 (0.44) TP53ALDH1A1HPGDALOX15ALOX12
SCHEMBL9422114 0.80 ALDH1A1 (0.45) TP53ALDH1A1HPGDALOX15ALOX12
SCHEMBL8382117 0.80 ALDH1A1 (0.44) TP53ALDH1A1HPGDALOX15ALOX12
SCHEMBL3482035 0.80 TDP1 (0.48) TP53ALDH1A1HPGDALOX15ALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 169 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115464145-A Metal nanocluster and preparation method and application thereof 中国科学院上海有机化学研究所 2022-12-13 CN claimed
CN-107406468-B Silicone-modified photoinitiators and photocurable adhesive compositions thereof 汉高股份有限及两合公司 2020-11-06 CN claimed
EP-3186263-B1 ORGANOSILICON MODIFIED PHOTOINITIATOR AND PHOTO-CURABLE ADHESIVE COMPOSITION THEREOF HENKEL AG & CO KGAA (DE) 2020-04-22 EP claimed
US-10189867-B2 Organosilicon modified photoinitiator and a photo-curable adhesive composition comprising the same Henkel IP & Holding GmbH (DE) 2019-01-29 US claimed
CN-109225140-A A kind of modification is except formaldehyde zeolite and preparation method thereof 常州良福朗清生物科技有限公司 2019-01-18 CN claimed
US-20170283368-A1 METHODS FOR SYNTHESIZING SUBSTITUTED TETRACYCLINE COMPOUNDS PARATEK PHARMACEUTICALS, INC. 2017-10-05 US claimed
EP-3186263-A1 ORGANOSILICON MODIFIED PHOTOINITIATOR AND PHOTO-CURABLE ADHESIVE COMPOSITION THEREOF Henkel AG & Co. KGaA (DE) 2017-07-05 EP claimed
US-20170166594-A1 Organosilicon modified photoinitiator and a photo-curable adhesive composition comprising the same HENKEL (CHINA) COMPANY LIMITED (CN) 2017-06-15 US claimed
WO-2016029439-A1 ORGANOSILICON MODIFIED PHOTOINITIATOR AND PHOTO-CURABLE ADHESIVE COMPOSITION THEREOF HENKEL (CHINA) COMPANY LIMITED (CN) 2016-03-03 WO claimed
CN-101146867-B Self-adhesive addition-crosslinking silicone rubber mixtures, method for the production thereof, method for the production of composite molded parts, and use thereof GE BAYER SILICONES GMBH & CO 2012-07-18 CN claimed
CN-101146867-A Self-adhesive addition-crosslinking silicone rubber mixtures, method for the production thereof, method for the production of composite molded parts, and use thereof GE BAYER SILICONES GMBH & CO (DE) 2008-03-19 CN claimed
US-20250340507-A1 METHODS FOR SYNTHESIZING SUBSTITUTED TETRACYCLINE COMPOUNDS PARATEK PHARM INNC (US) 2025-11-06 US disclosed
EP-4234643-A2 ANTIFOULING COMPOSITION Jotun A/S (NO) 2023-08-30 EP disclosed
CN-115464145-A Metal nanocluster and preparation method and application thereof 中国科学院上海有机化学研究所 2022-12-13 CN disclosed
CN-108070055-B Antifouling composition 佐敦公司 2022-10-04 CN disclosed
US-5625078-A Processes for the production of 13-ether derivatives of milbemycins and novel intermediates therefor SANKYO COMPANY, LIMITED (JP) 1997-04-29 US disclosed
US-5461168-A Processes for the production of 13-ether derivatives of milbemycins, and intermediates therefor SANKYO COMPANY, LIMITED (JP) 1995-10-24 US disclosed
EP-0594291-A1 Novel processes for the production of 13-ether derivatives of milbemycins, and novel intermediates therefor SANKYO COMPANY LIMITED (JP) 1994-04-27 EP disclosed
EP-0246053-B1 UNSATURATED SILYLATED VINYL ALCOHOL POLYMERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-05-15 EP disclosed
US-4656221-A SOLVENT-FREE POLYSILOXANE COATINGS; RADIATION TRANSPARENT FOR USE ON COLORLESS BEVERAGE BOTTLES TOSHIBA SILICONE CO., LTD. (JP) 1987-04-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10189867-B2 Organosilicon modified photoinitiator and a photo-curable adhesive composition comprising the same ITGB2, ITGB8, C3AR1 TP53 2408/4885ALDH1A1 1399/4885HPGD 4528/4885
US-20250340507-A1 METHODS FOR SYNTHESIZING SUBSTITUTED TETRACYCLINE COMPOUNDS TET3, TET1, DHFR TP53 2186/4885ALDH1A1 4075/4885HPGD 2506/4885
US-20170283368-A1 METHODS FOR SYNTHESIZING SUBSTITUTED TETRACYCLINE COMPOUNDS TET3, TET1, DHFR TP53 2186/4885ALDH1A1 4075/4885HPGD 2506/4885
US-20170166594-A1 Organosilicon modified photoinitiator and a photo-curable adhesive composition comprising the same ITGB2, ITGB8, C3AR1 TP53 2417/4885ALDH1A1 1378/4885HPGD 4507/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.