Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.72 |
| ▸ | NPC1 | O15118 | 7/20 | 0.72 |
| ▸ | POLB | P06746 | 2/20 | 0.72 |
| ▸ | MEN1 | O00255 | 3/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.71 |
| ▸ | HPGD | P15428 | 2/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.71 |
| ▸ | MAOB | P27338 | 1/20 | 0.71 |
| ▸ | TP53 | P04637 | 1/20 | 0.71 |
| ▸ | NAMPT | P43490 | 1/20 | 0.68 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.67 |
| ▸ | LSS | P48449 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.64 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.64 |
| ▸ | CA1 | P00915 | 1/20 | 0.64 |
| ▸ | CA2 | P00918 | 1/20 | 0.64 |
| ▸ | CNR1 | P21554 | 2/20 | 0.63 |
| ▸ | MTOR | P42345 | 1/20 | 0.62 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8177097 | 0.93 | RAB9A (0.72) | RAB9ANPC1POLBMEN1KMT2A | |
| SCHEMBL26098750 | 0.88 | RAB9A (0.66) | RAB9ANPC1POLBMEN1KMT2A | |
| SCHEMBL2831462 | 0.88 | NPC1 (0.77) | RAB9ANPC1POLBMEN1KMT2A | |
| SCHEMBL23747545 | 0.87 | RAB9A (0.73) | RAB9ANPC1POLBMEN1KMT2A | |
| SCHEMBL31274801 | 0.87 | EPHX2 (0.66) | RAB9ANPC1POLBMEN1KMT2A | |
| SCHEMBL23747730 | 0.86 | RORC (0.72) | RAB9ANPC1POLBMEN1KMT2A | |
| SCHEMBL19570474 | 0.86 | RORC (0.72) | RAB9ANPC1POLBMEN1KMT2A | |
| SCHEMBL13479675 | 0.85 | TP53 (0.73) | RAB9ANPC1POLBMEN1KMT2A | |
| SCHEMBL23727986 | 0.85 | RAB9A (0.75) | RAB9ANPC1POLBMEN1KMT2A | |
| SCHEMBL23727642 | 0.85 | RAB9A (0.75) | RAB9ANPC1POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112574070-B | Synthesis method of substituted urea compound | 西华大学 | 2022-11-08 | — | — | CN | disclosed |
| CN-112574070-A | Synthesis method of substituted urea compound | 西华大学 | 2021-03-30 | — | — | CN | disclosed |
| CN-103664704-B | A kind of synthetic N, the method for N '-disubstituted urea | NANJING UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2016-05-18 | — | — | CN | disclosed |
| CN-103664704-A | Method for synthesizing N,N'-disubstituent urea | UNIV NANJING SCIENCE & TECH | 2014-03-26 | — | — | CN | disclosed |