Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.77 |
| ▸ | RAB9A | P51151 | 5/20 | 0.77 |
| ▸ | MEN1 | O00255 | 2/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.77 |
| ▸ | POLB | P06746 | 1/20 | 0.77 |
| ▸ | MAOB | P27338 | 1/20 | 0.77 |
| ▸ | HTT | P42858 | 1/20 | 0.77 |
| ▸ | TP53 | P04637 | 1/20 | 0.77 |
| ▸ | HPGD | P15428 | 1/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.77 |
| ▸ | MAPT | P10636 | 3/20 | 0.71 |
| ▸ | CA2 | P00918 | 3/20 | 0.69 |
| ▸ | CA1 | P00915 | 2/20 | 0.69 |
| ▸ | CA12 | O43570 | 1/20 | 0.69 |
| ▸ | CA9 | Q16790 | 1/20 | 0.69 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.69 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.69 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.67 |
| ▸ | RORC | P51449 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14025738 | 0.93 | NPC1 (0.73) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL17000091 | 0.93 | NPC1 (0.73) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL2704691 | 0.91 | MAPT (0.66) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL20804368 | 0.90 | NPC1 (0.65) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL4743393 | 0.89 | NPC1 (0.73) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL22588922 | 0.89 | NPC1 (0.68) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL10133206 | 0.89 | ROCK2 (0.80) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL4744610 | 0.89 | NPC1 (0.69) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL7420189 | 0.88 | RAB9A (1.00) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL8177097 | 0.88 | RAB9A (0.72) | NPC1RAB9AMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080227999-A1 | Heterogeneous Supported Catalytic Carbamate Process | MOLZAHN DAVID C | 2008-09-18 | — | — | US | claimed |
| EP-1943214-A2 | HETEROGENEOUS SUPPORTED CATALYTIC CARBAMATE PROCESS | Dow Gloval Technologies Inc. (US) | 2008-07-16 | — | — | EP | claimed |
| WO-2007015852-A2 | HETEROGENEOUS SUPPORTED CATALYTIC CARBAMATE PROCESS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2007-02-08 | — | — | WO | claimed |
| WO-2001007431-A2 | BENZOTHIOPHENE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2001-02-01 | — | — | WO | claimed |
| EP-0805796-A1 | CELL ADHESION INHIBITORS | BIOGEN, INC. (US) | 1997-11-12 | — | — | EP | claimed |
| WO-1996022966-A1 | CELL ADHESION INHIBITORS | BIOGEN, INC. (US) | 1996-08-01 | — | — | WO | claimed |
| US-4699923-A | N-benzoyl-N'-phenylureas and their use for insect control | BASF AKTIENGESELLSCHAFT (DE) | 1987-10-13 | — | — | US | claimed |
| EP-0056124-B1 | N-BENZOYL N' PHENYLUREAS, PREPARATION AND USE THEREOF AS INSECTICIDES | BASF Aktiengesellschaft (DE) | 1984-06-27 | — | — | EP | claimed |
| JP-61093163-A | — | — | None | — | — | JP | disclosed |
| CN-117886718-B | Preparation method of high-selectivity asymmetric urea compound and asymmetric urea compound | 内蒙古工业大学 | 2024-05-24 | — | — | CN | disclosed |
| CN-117886718-A | Preparation method of high-selectivity asymmetric urea compound and asymmetric urea compound | 内蒙古工业大学 | 2024-04-16 | — | — | CN | disclosed |
| US-20230348396-A1 | HYDROXYBENZAMIDE DERIVATIVES AND METHODS OF USE IN TREATING DIABETES | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) | 2023-11-02 | — | — | US | disclosed |
| EP-4217412-A1 | WASTE MITIGATION METHODS AND MATERIALS | Finite Research Ltd (GB) | 2023-08-02 | — | — | EP | disclosed |
| CN-115353667-A | Method and material for reducing waste | 李蓁蓁 | 2022-11-18 | — | — | CN | disclosed |
| US-4520377-A | COLOR FORMING LAYER COMO/SED OF ELECTRON DONATING COLORLESS DYE, ELECTRON ACCEPTING COMPOUND, NAPHTHOL UREA AND/OR URETHANE DERIVATIVE | FUJI PHOTO FILM CO., LTD. (JP) | 1985-05-28 | — | — | US | disclosed |
| US-4435567-A | REACTING AN AMINE WITH AN N-CARBAMOYL BENZOIC ACID SULFIMIDE | CHINOIN GYOGYSZER ES VESGYESZETI TERMEKEK GYARA R. T. (HU) | 1984-03-06 | — | — | US | disclosed |
| US-4401717-A | CONTAINING A CHROMOGEN, A PHENOL LAND A UREA OR CARBAMATE; THERMOGRAPHY | FUJI PHOTO FILM CO., LTD. (JP) | 1983-08-30 | — | — | US | disclosed |
| US-4220571-A | Thermoplastic polyolefin composition and process for stabilizing polyolefins | CIBA-GEIGY CORPORATION (US) | 1980-09-02 | — | — | US | disclosed |
| US-4122090-A | Cyclic esters of 3,4-dihydroxy-thiophene-1,1-dioxide compounds and 3,4-dihydroxy-cyclopentadienone compounds | BASF AKTIENGESELLSCHAFT (DE) | 1978-10-24 | — | — | US | disclosed |
| US-4089860-A | Preparation of hydantoins by reacting esters of ethylene-1,2-dicarboxylic acids and ureas and thioureas | BAYER AKTIENGESELLSCHAFT (DT) | 1978-05-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080227999-A1 | Heterogeneous Supported Catalytic Carbamate Process | CPS1, CAT, CA7 | NPC1 3549/4885RAB9A 1660/4885MEN1 1538/4885 |
| US-20230348396-A1 | HYDROXYBENZAMIDE DERIVATIVES AND METHODS OF USE IN TREATING DIABETES | HSPA5, IAPP, TFEB | NPC1 2361/4885RAB9A 3298/4885MEN1 4857/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.