SCHEMBL27953255

SCHEMBL27953255

O=C(O)C1(COCc2ccccc2)CCNCC1

nearest known ligand 0.64

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TACR1 P25103 13/20 0.64
SLC6A4 P31645 3/20 0.47
KCNH2 Q12809 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21496636 0.89 TACR1 (0.51) TACR1
SCHEMBL2435076 0.84 TACR1 (0.48) TACR1
SCHEMBL6522997 0.84 OPRM1 (0.56) TACR1
SCHEMBL8000886 0.82 TSHR (0.48) TACR1
SCHEMBL19838496 0.82 TACR1 (0.47) TACR1SLC6A4KCNH2
SCHEMBL15105750 0.82 TACR1 (0.46) TACR1
SCHEMBL7660076 0.80 TACR1 (0.65) TACR1SLC6A4KCNH2
SCHEMBL19839312 0.79 HTR2C (0.44) TACR1
SCHEMBL27719248 0.79 ALDH1A1 (0.49) TACR1SLC6A4
SCHEMBL1919144 0.79 SLC6A2 (0.56) TACR1SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103619838-B Piperidinyl monocarboxylic acids as S1P1 receptor agonists 生物计划公司 2016-08-24 CN disclosed
CN-103619838-A Novel piperidinyl monocarboxylic acids as s1p1 receptor agonists BIOPROJET SOC CIV 2014-03-05 CN disclosed