Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.56 |
| ▸ | TACR1 | P25103 | 9/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27498738 | 0.91 | LMNA (0.49) | OPRM1LMNAMEN1NPC1POLB | |
| SCHEMBL9875164 | 0.88 | KDM4E (0.50) | LMNAMEN1NPC1POLBRAB9A | |
| SCHEMBL19839917 | 0.87 | KDM4E (0.49) | LMNAMEN1NPC1POLBRAB9A | |
| SCHEMBL18650 | 0.85 | LMNA (0.45) | OPRM1LMNAMEN1NPC1POLB | |
| SCHEMBL12140572 | 0.85 | LMNA (0.45) | OPRM1LMNAMEN1NPC1POLB | |
| SCHEMBL962133 | 0.84 | OPRM1 (0.62) | OPRM1LMNAMEN1NPC1RAB9A | |
| SCHEMBL27953255 | 0.84 | TACR1 (0.64) | TACR1 | |
| SCHEMBL1919601 | 0.82 | MEN1 (0.61) | OPRM1LMNAMEN1NPC1POLB | |
| SCHEMBL18063140 | 0.81 | KDM4E (0.45) | LMNAMEN1NPC1POLBRAB9A | |
| SCHEMBL18063293 | 0.81 | LMNA (0.43) | LMNAMEN1NPC1POLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170283530-A1 | CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND APPLICATION THEREOF | BEIJING LIHE TECH LTD (CN) | 2017-10-05 | — | — | US | claimed |
| US-20160272733-A1 | CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND APPLICATION THEREOF | BEIJING LIHE TECHNOLOGY LTD. (CN) | 2016-09-22 | — | — | US | claimed |
| US-20190169328-A1 | OLEFIN POLYMERIZATION CATALYST CARRIER, SOLID CATALYST COMPONENT AND USE THEREOF | RENQIU LIHE TECH LTD (CN) | 2019-06-06 | — | — | US | disclosed |
| US-10208146-B2 | Catalyst component for olefin polymerization and application thereof | BEIJING LIHE TECHNOLOGY LTD. (CN) | 2019-02-19 | — | — | US | disclosed |
| US-20170355792-A1 | OLEFIN POLYMERIZATION CATALYST CARRIER, SOLID CATALYST COMPONENT AND USE THEREOF | RENQIU LIHE TECH LTD (CN) | 2017-12-14 | — | — | US | disclosed |
| US-20170283530-A1 | CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND APPLICATION THEREOF | BEIJING LIHE TECH LTD (CN) | 2017-10-05 | — | — | US | disclosed |
| US-20160272733-A1 | CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND APPLICATION THEREOF | BEIJING LIHE TECHNOLOGY LTD. (CN) | 2016-09-22 | — | — | US | disclosed |
| US-9266867-B2 | Piperidinyl monocarboxylic acids as S1P1 receptor agonists | BIOPROJET (FR) | 2016-02-23 | — | — | US | disclosed |
| EP-2697219-B1 | NOVEL PIPERIDINYL MONOCARBOXYLIC ACIDS AS S1P1 RECEPTOR AGONISTS | BIOPROJET SOC CIV (FR) | 2015-03-04 | — | — | EP | disclosed |
| EP-2697219-B1 | NOVEL PIPERIDINYL MONOCARBOXYLIC ACIDS AS S1P1 RECEPTOR AGONISTS | BIOPROJET SOC CIV (FR) | 2015-03-04 | — | — | EP | disclosed |
| US-20140099316-A1 | NOVEL PIPERIDINYL MONOCARBOXYLIC ACIDS AS S1P1 RECEPTOR AGONISTS | SUN PHARMA ADVANCED RESEARCH COMPANY LTD. (IN) | 2014-04-10 | — | — | US | disclosed |
| EP-2475644-B1 | HSL INHIBITORS USEFUL IN THE TREATMENT OF DIABETES | HOFFMANN LA ROCHE (CH) | 2014-01-08 | — | — | EP | disclosed |
| WO-2012140020-A1 | NOVEL PIPERIDINYL MONOCARBOXYLIC ACIDS AS S1P1 RECEPTOR AGONISTS | BIOPROJET (FR) | 2012-10-18 | — | — | WO | disclosed |
| WO-2012140020-A1 | NOVEL PIPERIDINYL MONOCARBOXYLIC ACIDS AS S1P1 RECEPTOR AGONISTS | BIOPROJET (FR) | 2012-10-18 | — | — | WO | disclosed |
| EP-2511275-A1 | Novel piperidinyl monocarboxylic acids as S1P1 receptor agonists | BIOPROJET (FR) | 2012-10-17 | — | — | EP | disclosed |
| EP-2511275-A1 | Novel piperidinyl monocarboxylic acids as S1P1 receptor agonists | BIOPROJET (FR) | 2012-10-17 | — | — | EP | disclosed |
| US-8258158-B2 | HSL inhibitors useful in the treatment of diabetes | HOFFMANN-LA ROCHE INC. (US) | 2012-09-04 | — | — | US | disclosed |
| EP-2475644-A1 | HSL INHIBITORS USEFUL IN THE TREATMENT OF DIABETES | F. Hoffmann-La Roche AG (CH) | 2012-07-18 | — | — | EP | disclosed |
| WO-2011029808-A1 | HSL INHIBITORS USEFUL IN THE TREATMENT OF DIABETES | F. HOFFMANN-LA ROCHE AG (CH) | 2011-03-17 | — | — | WO | disclosed |
| US-20110065707-A1 | NEW HSL INHIBITORS USEFUL IN THE TREATMENT OF DIABETES | HOFFMANN-LA ROCHE, INC. | 2011-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10208146-B2 | Catalyst component for olefin polymerization and application thereof | TEC, ETFA, TECR | OPRM1 303/4885TACR1 3907/4885LMNA 4452/4885 |
| US-20190169328-A1 | OLEFIN POLYMERIZATION CATALYST CARRIER, SOLID CATALYST COMPONENT AND USE THEREOF | COG2, GTF2I, POF1B | OPRM1 13/4885TACR1 4062/4885LMNA 2302/4885 |
| US-20170283530-A1 | CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND APPLICATION THEREOF | TEC, ETFA, TECR | OPRM1 303/4885TACR1 3907/4885LMNA 4452/4885 |
| US-20110065707-A1 | NEW HSL INHIBITORS USEFUL IN THE TREATMENT OF DIABETES | LIPE, PNLIP, LPL | OPRM1 3861/4885TACR1 760/4885LMNA 779/4885 |
| US-20140099316-A1 | NOVEL PIPERIDINYL MONOCARBOXYLIC ACIDS AS S1P1 RECEPTOR AGONISTS | S1PR1, S1PR3, S1PR2 | OPRM1 588/4885TACR1 104/4885LMNA 2469/4885 |
| US-20170355792-A1 | OLEFIN POLYMERIZATION CATALYST CARRIER, SOLID CATALYST COMPONENT AND USE THEREOF | COG2, COG7, COG4 | OPRM1 118/4885TACR1 3287/4885LMNA 3701/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.