Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | PIK3C2B | O00750 | 4/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | YES1 | P07947 | 1/20 | 0.39 |
| ▸ | FGR | P09769 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | EEF2K | O00418 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 2/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | STK4 | Q13043 | 1/20 | 0.37 |
| ▸ | STK3 | Q13188 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28808532 | 0.88 | LRRK2 (0.42) | GAAKDM4EPIK3C2BPIK3CGALDH1A1 | |
| SCHEMBL27953704 | 0.86 | LRRK2 (0.41) | PIK3C2BPIK3CGALDH1A1YES1FGR | |
| SCHEMBL28406676 | 0.71 | ADK (0.50) | KDM4EPIK3CGMEN1KMT2ASRC | |
| SCHEMBL16655310 | 0.71 | PIK3CD (0.50) | GAAKDM4EPIK3CD | |
| Hydrochloric Acid SCHEMBL23908596 | 0.70 | PIK3CD (0.49) | GAAKDM4EPIK3CD | |
| SCHEMBL4824834 | 0.70 | LRRK2 (0.47) | GAAKDM4EALDH1A1PIK3CAJAK3 | |
| SCHEMBL27943325 | 0.69 | PIK3CD (0.40) | KDM4EPIK3C2BPIK3CGMEN1KMT2A | |
| SCHEMBL27943334 | 0.68 | LRRK2 (0.43) | KDM4EPIK3CGMEN1KMT2AYES1 | |
| SCHEMBL1439667 | 0.68 | KDM4E (0.58) | GAAKDM4EPIK3CDPIK3CAPIK3CB | |
| SCHEMBL17623135 | 0.66 | KDM4E (0.70) | GAAKDM4EMEN1KMT2APIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103702989-A | Novel compounds as modulators of protein kinases | RHIZEN PHARMACEUTICALS SA | 2014-04-02 | — | — | CN | claimed |
| CN-103702989-A | Novel compounds as modulators of protein kinases | RHIZEN PHARMACEUTICALS SA | 2014-04-02 | — | — | CN | disclosed |