Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 7/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 5/20 | 0.37 |
| ▸ | YES1 | P07947 | 4/20 | 0.37 |
| ▸ | FGR | P09769 | 4/20 | 0.37 |
| ▸ | LYN | P07948 | 2/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.37 |
| ▸ | PRKDC | P78527 | 4/20 | 0.37 |
| ▸ | ABL1 | P00519 | 3/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | FRK | P42685 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27943325 | 0.77 | PIK3CD (0.40) | CYP1A2MAPK1KDM4ETP53CYP3A4 | |
| SCHEMBL28406676 | 0.76 | ADK (0.50) | CYP1A2MAPK1KDM4ETP53CYP3A4 | |
| SCHEMBL27943335 | 0.72 | PIK3CD (0.50) | CYP1A2MAPK1KDM4ETP53CYP3A4 | |
| SCHEMBL28808532 | 0.71 | LRRK2 (0.42) | LRRK2KDM4ESRCYES1FGR | |
| SCHEMBL3785235 | 0.70 | PIK3CD (0.51) | MAPK1KDM4EFYNSRCPIK3CD | |
| SCHEMBL27953704 | 0.70 | LRRK2 (0.41) | LRRK2SRCYES1FGRPIK3CD | |
| SCHEMBL27943341 | 0.68 | PIK3CD (0.44) | CYP1A2MAPK1KDM4ETP53CYP3A4 | |
| SCHEMBL27953708 | 0.68 | GAA (0.51) | KDM4EMEN1KMT2ASRCYES1 | |
| SCHEMBL8324823 | 0.68 | ADK (0.71) | — | |
| SCHEMBL27953706 | 0.67 | PIK3CG (0.57) | CYP1A2MAPK1KDM4ETP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103702989-A | Novel compounds as modulators of protein kinases | RHIZEN PHARMACEUTICALS SA | 2014-04-02 | — | — | CN | claimed |
| CN-103702989-A | Novel compounds as modulators of protein kinases | RHIZEN PHARMACEUTICALS SA | 2014-04-02 | — | — | CN | disclosed |