Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1770287 | 0.80 | TP53 (0.38) | TP53L3MBTL1ALOX5APFEN1KDM4E | |
| SCHEMBL13712974 | 0.77 | ALOX15 (0.50) | TP53ALOX5APFEN1HSD17B10GFER | |
| SCHEMBL1771075 | 0.74 | TP53 (0.40) | TP53L3MBTL1ALOX5APFEN1KDM4E | |
| SCHEMBL1023898 | 0.73 | L3MBTL1 (0.61) | TP53L3MBTL1KMT2ALMNAMEN1 | |
| SCHEMBL27955975 | 0.73 | MEN1 (0.43) | TP53L3MBTL1KMT2AMEN1 | |
| SCHEMBL12545906 | 0.73 | ALOX15 (0.49) | TP53HSD17B10GFER | |
| SCHEMBL28334325 | 0.73 | TP53 (0.47) | TP53L3MBTL1KDM4EGAAKMT2A | |
| SCHEMBL1770648 | 0.72 | F2 (0.42) | TP53L3MBTL1KDM4EGAAKMT2A | |
| SCHEMBL22997585 | 0.72 | HSD17B10 (0.44) | TP53L3MBTL1ALOX5APFEN1KDM4E | |
| SCHEMBL3770108 | 0.72 | MEN1 (0.63) | TP53ALOX5APFEN1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102015675-B | Chlorothiophene-amides as inhibitors of coagulation factors Xa and thrombin | SANOFI AVENTIS | 2014-07-02 | — | — | CN | disclosed |