Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALPG | P10696 | 1/20 | 0.41 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CETP | P11597 | 3/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL389123 | 0.82 | TSHR (0.61) | TSHRMEN1KMT2AALPGPTK2B | |
| SCHEMBL28104834 | 0.81 | TSHR (0.59) | TSHRMEN1KMT2AALPGPTK2B | |
| SCHEMBL27956679 | 0.81 | TSHR (0.47) | TSHRMEN1KMT2AALPGPTK2B | |
| SCHEMBL28519668 | 0.80 | TSHR (0.50) | TSHRMEN1KMT2ACETPPDPK1 | |
| SCHEMBL28519236 | 0.78 | MEN1 (0.49) | TSHRMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL27956676 | 0.73 | MEN1 (0.51) | TSHRMEN1KMT2AL3MBTL1TDP1 | |
| SCHEMBL28449328 | 0.71 | KMT2A (0.49) | TSHRMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL28897993 | 0.71 | APP (0.50) | TSHRMEN1KMT2AL3MBTL1CETP | |
| SCHEMBL28454755 | 0.71 | MEN1 (0.53) | TSHRMEN1KMT2AL3MBTL1CETP | |
| SCHEMBL28453734 | 0.71 | KMT2A (0.49) | TSHRMEN1KMT2AL3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103980306-A | Preparation method for hypophosphorous acid / phosphorous acid/ phosphate compounds by adopting P(O)-OH-contained compounds | UNIV HUNAN | 2014-08-13 | — | — | CN | disclosed |