SCHEMBL27958720

SCHEMBL27958720

CC(Br)c1ccc(C=O)cc1Cl

nearest known ligand 0.53

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.53
TYR P14679 1/20 0.44
ALDH1A3 P47895 5/20 0.42
ALDH3A1 P30838 2/20 0.42
VCAM1 P19320 1/20 0.40
HSD17B10 Q99714 1/20 0.39
TSHR P16473 1/20 0.36
LMNA P02545 1/20 0.36
TP53 P04637 1/20 0.36
HTT P42858 1/20 0.36
KDM4E B2RXH2 1/20 0.35
PTGS2 P35354 1/20 0.35
RAB9A P51151 1/20 0.35
CYP2A6 P11509 1/20 0.34
PTGER4 P35408 1/20 0.34
TTR P02766 1/20 0.34
TACR2 P21452 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6015145 0.85 ALDH1A1 (0.57) ALDH1A1TYRALDH1A3ALDH3A1VCAM1
SCHEMBL21749312 0.74 ALDH1A1 (0.53) ALDH1A1TYRALDH1A3ALDH3A1VCAM1
SCHEMBL30664368 0.74 TP53 (0.63) ALDH1A1HSD17B10TSHRLMNATP53
SCHEMBL5252726 0.74 TP53 (0.63) ALDH1A1HSD17B10TSHRLMNATP53
SCHEMBL6015153 0.73 ALDH1A1 (0.57) ALDH1A1TYRALDH1A3ALDH3A1VCAM1
SCHEMBL18519788 0.73 ALDH1A1 (0.43) ALDH1A1TYRALDH1A3ALDH3A1VCAM1
SCHEMBL27490666 0.72 MAPK1 (0.41) ALDH1A1TSHRLMNATP53HTT
SCHEMBL18103225 0.72 LMNA (0.42) ALDH1A1LMNATP53HTTRAB9A
Ethane SCHEMBL2154115 0.72 ALDH1A1 (0.55) ALDH1A1TYRALDH1A3ALDH3A1VCAM1
SCHEMBL19970528 0.71 LMNA (0.39) LMNATP53HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103748089-A Pesticidal compositions and methods relating thereto DOW AGROSCIENCES LLC 2014-04-23 CN disclosed