Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 15/20 | 0.59 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | FLT3 | P36888 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27850347 | 0.81 | CYP19A1 (0.58) | CYP19A1HSP90AB1NPC1RAB9AALDH1A1 | |
| SCHEMBL28103690 | 0.78 | CYP19A1 (0.51) | CYP19A1HSP90AB1NPC1RAB9AALDH1A1 | |
| SCHEMBL27948913 | 0.77 | L3MBTL1 (0.51) | NPC1RAB9A | |
| SCHEMBL1242192 | 0.75 | CYP19A1 (0.61) | CYP19A1HSP90AB1NPC1RAB9AALDH1A1 | |
| SCHEMBL29230705 | 0.75 | ALDH1A1 (0.49) | CYP19A1HSP90AB1NPC1RAB9AALDH1A1 | |
| SCHEMBL2190939 | 0.75 | HSP90AB1 (0.82) | CYP19A1HSP90AB1NPC1RAB9A | |
| SCHEMBL22510634 | 0.74 | CYP19A1 (0.82) | CYP19A1NPC1RAB9AALDH1A1LMNA | |
| SCHEMBL84637 | 0.74 | CYP19A1 (1.00) | CYP19A1HSP90AB1 | |
| SCHEMBL20590794 | 0.74 | CYP19A1 (0.56) | CYP19A1NPC1RAB9AFLT3GSK3B | |
| SCHEMBL12673479 | 0.73 | CYP19A1 (0.76) | CYP19A1HSP90AB1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103772302-B | Carboxymethylation pulullan polysaccharide/cuprous oxide catalysis system catalyzes and synthesizes the method for 1,2,3-triazole compound | HENAN NORMAL UNIVERSITY (CN) | 2015-07-29 | — | — | CN | disclosed |
| CN-103772301-B | Method for catalytically synthesizing 1,2,3-triazole compound by using carboxylation nano-hydroxyapatite and cuprous oxide as catalytic systems | UNIV HENAN NORMAL | 2015-07-01 | — | — | CN | disclosed |
| CN-103772301-A | Method for catalytically synthesizing 1,2,3-triazole compound by using carboxylation nano-hydroxyapatite and cuprous oxide as catalytic systems | UNIV HENAN NORMAL | 2014-05-07 | — | — | CN | disclosed |
| CN-103772302-A | Method of catalyzed synthesis of 1, 2, 3-triazole compounds by carboxymethylated Pulullan/cuprous oxide catalytic system | UNIV HENAN NORMAL | 2014-05-07 | — | — | CN | disclosed |