Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3614755 | 0.85 | GRM5 (0.39) | GRM5ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1375869 | 0.80 | GRM5 (0.53) | GRM5ALDH1A1MAPK1 | |
| SCHEMBL29779956 | 0.80 | GRM5 (0.53) | GRM5ALDH1A1MAPK1 | |
| SCHEMBL26988477 | 0.79 | GRM5 (0.44) | GRM5ALDH1A1MAPK1GABRA1GABRG2 | |
| SCHEMBL18704185 | 0.79 | LOX (0.31) | — | |
| SCHEMBL23867871 | 0.78 | APP (0.50) | GRM5ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3347354 | 0.78 | GRM5 (0.56) | GRM5SMN1; SMN2GABRA1GABRG2GABRB3 | |
| SCHEMBL31349195 | 0.78 | GRM5 (0.56) | GRM5SMN1; SMN2GABRA1GABRG2GABRB3 | |
| SCHEMBL4737005 | 0.77 | GRM5 (0.49) | GRM5ALDH1A1MAPK1NPC1RAB9A | |
| SCHEMBL4769651 | 0.77 | GRM5 (0.47) | GRM5ALDH1A1MAPK1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119490480-A | Isophenyl bridged alkynyl pyrazole pyridine derivative and preparation method and application thereof | 北京工业大学 | 2025-02-21 | — | — | CN | claimed |
| CN-117659017-B | TRPML1/2 modulator compound, pharmaceutical composition, preparation method and application thereof | 北京华益健康药物研究中心 | 2026-05-15 | — | — | CN | disclosed |
| CN-119490480-A | Isophenyl bridged alkynyl pyrazole pyridine derivative and preparation method and application thereof | 北京工业大学 | 2025-02-21 | — | — | CN | disclosed |
| CN-117659017-A | TRPML1/2 modulator compound, pharmaceutical composition, preparation method and application thereof | 北京华益健康药物研究中心 | 2024-03-08 | — | — | CN | disclosed |
| WO-2024002379-A1 | COMPOUND USED AS WDR5 INHIBITOR OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND USE OF COMPOUND | 甘李药业股份有限公司 | 2024-01-04 | — | — | WO | disclosed |
| US-20230183203-A1 | ANTIBACTERIAL COMPOUNDS | THE PENN STATE RESEARCH FOUNDATION | 2023-06-15 | — | — | US | disclosed |
| US-20230183203-A1 | ANTIBACTERIAL COMPOUNDS | THE PENN STATE RESEARCH FOUNDATION | 2023-06-15 | — | — | US | disclosed |
| US-11634447-B2 | Mannose derivatives for treating bacterial infections | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2023-04-25 | — | — | US | disclosed |
| EP-4157265-A1 | ANTIBACTERIAL COMPOUNDS | THE PENN STATE RESEARCH FOUNDATION (US) | 2023-04-05 | — | — | EP | disclosed |
| US-20220135609-A1 | Mannose Derivatives for Treating Bacterial Infections | VERTEX PHARMA (US) | 2022-05-05 | — | — | US | disclosed |
| US-5645809-A | ELECTRODES | OHIO STATE UNIVERSITY (US) | 1997-07-08 | — | — | US | disclosed |
| US-5453169-A | Particle sizes for electrodes | THE OHIO STATE UNIVERSITY (US) | 1995-09-26 | — | — | US | disclosed |
| WO-1994019515-A1 | GLASSY CARBON CONTAINING METAL PARTICLES | THE OHIO STATE UNIVERSITY (US) | 1994-09-01 | — | — | WO | disclosed |
| US-5329036-A | (alpha, omega)phenylethynyl siloxane monomers, oligomers, and polymers thereof | HUGHES AIRCRAFT COMPANY (US) | 1994-07-12 | — | — | US | disclosed |
| US-5329036-A | (alpha, omega)phenylethynyl siloxane monomers, oligomers, and polymers thereof | HUGHES AIRCRAFT COMPANY (US) | 1994-07-12 | — | — | US | disclosed |
| EP-0585590-A1 | (Alpha, omega) phenylethynyl siloxane monomers, oligomers, and polymers thereof | Hughes Aircraft Company (US) | 1994-03-09 | — | — | EP | disclosed |
| EP-0585590-A1 | (Alpha, omega) phenylethynyl siloxane monomers, oligomers, and polymers thereof | Hughes Aircraft Company (US) | 1994-03-09 | — | — | EP | disclosed |
| US-4912097-A | Novel 11 β-alkynylphenyl-10-nor-steroids | ROUSSEL UCLAF (FR) | 1990-03-27 | — | — | US | disclosed |
| EP-0245170-B1 | 19-NOR OR 19-NOR D-HOMO STEROIDS SUBSTITUTED AT POSITION 11 BETA BY A PHENYL GROUP SUBSTITUTED BY AN ALKYNYL GROUP, PROCESS FOR THEIR PREPARATION, THEIR USE IN MEDICAMENTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ROUSSEL-UCLAF (FR) | 1989-11-29 | — | — | EP | disclosed |
| EP-0245170-A1 | 19-Nor or 19-nor D-homo steroids substituted at position 11 beta by a phenyl group substituted by an alkynyl group, process for their preparation, their use in medicaments and pharmaceutical compositions containing them | ROUSSEL-UCLAF (FR) | 1987-11-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220135609-A1 | Mannose Derivatives for Treating Bacterial Infections | MPI, MANBA, MAN2A1 | GRM5 2033/4885ALDH1A1 1603/4885MAPK1 614/4885 |
| US-20230183203-A1 | ANTIBACTERIAL COMPOUNDS | MRPL21, CLPP, SPOUT1 | GRM5 4698/4885ALDH1A1 3840/4885MAPK1 4003/4885 |
| US-11634447-B2 | Mannose derivatives for treating bacterial infections | MPI, MANBA, MAN2A1 | GRM5 2033/4885ALDH1A1 1603/4885MAPK1 614/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.