Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | AGTR1 | P30556 | 16/20 | 0.54 |
| ▸ | LTB4R2 | Q9NPC1 | 4/20 | 0.54 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.54 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.54 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2795 | 1.00 | ALDH1A1 (0.54) | ALDH1A1LMNAPOLBHSD17B10L3MBTL1 | |
| SCHEMBL3117 | 0.93 | AGTR1 (0.52) | ALDH1A1LMNAPOLBHSD17B10L3MBTL1 | |
| SCHEMBL3048 | 0.93 | AGTR1 (0.52) | ALDH1A1LMNAPOLBHSD17B10L3MBTL1 | |
| SCHEMBL8482053 | 0.91 | ALDH1A1 (0.46) | ALDH1A1LMNAPOLBHSD17B10L3MBTL1 | |
| SCHEMBL3085 | 0.91 | AGTR1 (0.55) | ALDH1A1LMNAPOLBHSD17B10L3MBTL1 | |
| SCHEMBL2423 | 0.91 | AGTR1 (0.55) | ALDH1A1LMNAPOLBHSD17B10L3MBTL1 | |
| SCHEMBL2482 | 0.91 | ALDH1A1 (0.47) | ALDH1A1LMNAPOLBHSD17B10L3MBTL1 | |
| SCHEMBL3011 | 0.91 | AGTR1 (0.51) | ALDH1A1LMNAPOLBHSD17B10L3MBTL1 | |
| SCHEMBL3185 | 0.91 | AGTR1 (0.51) | ALDH1A1LMNAPOLBHSD17B10L3MBTL1 | |
| SCHEMBL28455057 | 0.90 | AGTR1 (0.58) | ALDH1A1LMNAPOLBHSD17B10L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0443983-B1 | Acyl compounds | CIBA GEIGY AG (CH) | 1996-02-28 | — | — | EP | claimed |
| US-5399578-A | Hypotensive; valsartan; high blood pressure and cardiac insufficiency | CIBA-GEIGY CORP (US) | 1995-03-21 | — | — | US | disclosed |