SCHEMBL27960587

SCHEMBL27960587

O=COc1cccnc1Cl

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.41
LMNA P02545 2/20 0.41
NFE2L2 Q16236 5/20 0.39
TRIM24 O15164 1/20 0.38
TRIM33 Q9UPN9 1/20 0.38
CHRNB2 P17787 3/20 0.38
CHRNA4 P43681 3/20 0.38
NPC1 O15118 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
ALDH1A1 P00352 4/20 0.36
KDM4E B2RXH2 2/20 0.36
POLB P06746 2/20 0.36
RECQL P46063 1/20 0.36
HPGD P15428 1/20 0.35
HTT P42858 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formic Acid Methyl Ester SCHEMBL27958586 0.79 NFE2L2 (0.49) LMNANFE2L2NPC1L3MBTL1ALDH1A1
SCHEMBL16586557 0.76 LMNA (0.43) SMN1; SMN2LMNANFE2L2CHRNB2CHRNA4
SCHEMBL14903435 0.76 ERN1 (0.36) LMNATRIM24TRIM33NPC1L3MBTL1
SCHEMBL10121812 0.76 LTA4H (0.49) SMN1; SMN2TRIM24TRIM33NPC1L3MBTL1
Formic Acid SCHEMBL28048184 0.76 NFE2L2 (0.49) SMN1; SMN2LMNANFE2L2NPC1L3MBTL1
SCHEMBL5319328 0.74 LMNA (0.53) SMN1; SMN2LMNANFE2L2TRIM24TRIM33
SCHEMBL25552636 0.73 CHRNB4 (0.42) NFE2L2NPC1ALDH1A1
SCHEMBL28234 0.73 KDM4E (0.53) SMN1; SMN2LMNANPC1L3MBTL1KDM4E
SCHEMBL31567831 0.73 CYP11B1 (0.46) ALDH1A1KDM4EHTT
SCHEMBL7056120 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106751942-A A kind of super abrasive static-free glue band 郑州源冉生物技术有限公司 2017-05-31 CN claimed
CN-106753010-A A kind of acid and alkali-resistance High temperature-resistanadhesive adhesive tape 郑州北斗七星通讯科技有限公司 2017-05-31 CN claimed
CN-106753090-A A kind of wear-resisting static-free glue band 郑州源冉生物技术有限公司 2017-05-31 CN claimed
CN-106751942-A A kind of super abrasive static-free glue band 郑州源冉生物技术有限公司 2017-05-31 CN disclosed
CN-106753090-A A kind of wear-resisting static-free glue band 郑州源冉生物技术有限公司 2017-05-31 CN disclosed
CN-106753010-A A kind of acid and alkali-resistance High temperature-resistanadhesive adhesive tape 郑州北斗七星通讯科技有限公司 2017-05-31 CN disclosed
CN-106432232-A Synthesis method of 1-piperidin-4-yl-1,3-dihydro-imidazol[4, 5-b]pyridine-2-one 苏州汉德创宏生化科技有限公司 2017-02-22 CN disclosed
CN-102712590-B Production method of 2-chloro-3-trifluoromethylpyridine ISHIHARA SANGYO KAISHA 2014-04-30 CN disclosed