Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PABPC1 | P11940 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.34 |
| ▸ | MEN1 | O00255 | 5/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | P4HTM | Q9NXG6 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | DDX3X | O00571 | 1/20 | 0.33 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.33 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16246131 | 0.79 | TRPV1 (0.39) | PABPC1KMT2AMEN1MAPTKDM4E | |
| SCHEMBL16246243 | 0.77 | DDX3X (0.38) | KMT2AMEN1MAPTKDM4EP4HTM | |
| SCHEMBL20607583 | 0.76 | AR (0.35) | KMT2AMEN1MAPTKDM4EP4HTM | |
| SCHEMBL1900631 | 0.75 | PDE7A (0.41) | PABPC1KMT2AMEN1MAPTKDM4E | |
| SCHEMBL16881120 | 0.73 | P4HTM (0.39) | PABPC1NPSR1KMT2AMEN1MAPT | |
| SCHEMBL17784989 | 0.72 | TRPV1 (0.43) | KMT2AMEN1MAPTKDM4EP4HTM | |
| SCHEMBL16423725 | 0.71 | NAMPT (0.39) | LMNAKMT2AMEN1MAPTKDM4E | |
| SCHEMBL17785022 | 0.70 | DGAT1 (0.40) | PABPC1LMNANPSR1KMT2AMEN1 | |
| SCHEMBL27961472 | 0.69 | PDCD1 (0.42) | PABPC1KMT2AMEN1MAPTKDM4E | |
| SCHEMBL28292574 | 0.69 | P4HTM (0.41) | PABPC1KMT2AMEN1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103842357-A | Substituted heteroaromatic pyrazole-containing carboxamide and urea compounds as vanilloid receptor ligands | GRUENENTHAL GMBH | 2014-06-04 | — | — | CN | disclosed |