Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 3/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | P2RY13 | Q9BPV8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14659934 | 0.84 | FAAH (0.47) | KDM4EMEN1KMT2AMAPTRAB9A | |
| SCHEMBL17785022 | 0.80 | DGAT1 (0.40) | KDM4EMEN1KMT2AMAPTPABPC1 | |
| SCHEMBL14665823 | 0.78 | L3MBTL1 (0.42) | PDCD1CD274KDM4EMEN1KMT2A | |
| SCHEMBL27961403 | 0.78 | HCAR3 (0.66) | KDM4EMEN1KMT2AMAPTHCAR3 | |
| SCHEMBL17409833 | 0.76 | TLR7 (0.46) | PDCD1CD274KDM4EMEN1KMT2A | |
| SCHEMBL27961476 | 0.74 | KMT2A (0.51) | KDM4EMEN1KMT2AMAPTNAMPT | |
| SCHEMBL14659877 | 0.74 | TLR7 (0.42) | PDCD1CD274KDM4EHCAR3ALDH1A1 | |
| SCHEMBL28045441 | 0.73 | PDCD1 (0.39) | PDCD1CD274KDM4ENAMPTSMN1; SMN2 | |
| SCHEMBL1900631 | 0.73 | PDE7A (0.41) | KDM4EMEN1KMT2AMAPTPABPC1 | |
| SCHEMBL17403532 | 0.71 | KMT2A (0.39) | KDM4EMEN1KMT2AMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103842357-A | Substituted heteroaromatic pyrazole-containing carboxamide and urea compounds as vanilloid receptor ligands | GRUENENTHAL GMBH | 2014-06-04 | — | — | CN | disclosed |