SCHEMBL27962452

SCHEMBL27962452

CCC(=O)OC(=O)C(F)CC

nearest known ligand 0.35

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.35
ALDH1A1 P00352 4/20 0.33
HIF1A Q16665 2/20 0.33
MGAM O43451 1/20 0.33
GAA P10253 1/20 0.33
SI P14410 1/20 0.33
MGAM2 Q2M2H8 1/20 0.33
ESR1 P03372 1/20 0.33
SOAT1 P35610 1/20 0.33
CYP1A2 P05177 1/20 0.32
HPGD P15428 1/20 0.32
CYP2C19 P33261 1/20 0.32
BLM P54132 1/20 0.32
WRN Q14191 1/20 0.32
TRPA1 O75762 1/20 0.31
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10413543 0.87 SOAT1 (0.38) NAAAALDH1A1MGAMGAASI
SCHEMBL10413547 0.85 ALDH1A1 (0.56) NAAAALDH1A1MAPT
SCHEMBL775414 0.84 NAAA (0.34) NAAAALDH1A1HIF1AMGAMGAA
SCHEMBL775327 0.78 NAAA (0.37) NAAAALDH1A1HIF1AMGAMGAA
SCHEMBL10756871 0.77 ALDH1A1 (0.35) ALDH1A1MGAMGAASIMGAM2
SCHEMBL576407 0.77 NAAA (0.31) NAAA
SCHEMBL29180360 0.76 NAAA (0.35) NAAAALDH1A1HIF1AMGAMGAA
SCHEMBL777080 0.76 NAAA (0.35) NAAAALDH1A1HIF1AMGAMGAA
SCHEMBL681192 0.76 NAAA (0.52) NAAAALDH1A1HIF1AMGAMGAA
SCHEMBL4631695 0.75 CA2 (0.40) NAAAALDH1A1HIF1AMGAMGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118307408-A Preparation method of ethyl 2-fluoropropionylacetate 上海恩氟佳科技有限公司 2024-07-09 CN disclosed
CN-118307408-A Preparation method of ethyl 2-fluoropropionylacetate 上海恩氟佳科技有限公司 2024-07-09 CN disclosed
CN-118125982-A Synthesis method of 5-fluoro-6-ethyl-4-hydroxypyrimidine 风火轮(上海)生物科技有限公司 2024-06-04 CN disclosed
CN-103896855-A Method for synthesizing 4-(1-bromoethyl) -5-fluoro-6-chloropyrimidine JUHUA GROUP TECHNOLOGY CT 2014-07-02 CN disclosed