Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3E | A5X5Y0 | 8/20 | 0.38 |
| ▸ | HTR3B | O95264 | 8/20 | 0.38 |
| ▸ | HTR3A | P46098 | 8/20 | 0.38 |
| ▸ | HTR3D | Q70Z44 | 8/20 | 0.38 |
| ▸ | HTR3C | Q8WXA8 | 8/20 | 0.38 |
| ▸ | UBE2M | P61081 | 1/20 | 0.38 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.38 |
| ▸ | TAF1 | P21675 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2799030 | 0.93 | UBE2M (0.38) | UBE2MDCUN1D1LMNAALDH1A1TP53 | |
| SCHEMBL2800004 | 0.92 | TAF1 (0.41) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL2796663 | 0.90 | TAF1 (0.39) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL2795743 | 0.89 | UBE2M (0.39) | UBE2MDCUN1D1LMNAALDH1A1MAPK1 | |
| SCHEMBL5046677 | 0.88 | LMNA (0.45) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL2800239 | 0.85 | LMNA (0.40) | UBE2MDCUN1D1LMNAALDH1A1 | |
| SCHEMBL2798616 | 0.85 | UBE2M (0.38) | UBE2MDCUN1D1LMNAALDH1A1TP53 | |
| SCHEMBL2798834 | 0.85 | UBE2M (0.36) | UBE2MDCUN1D1LMNASMN1; SMN2NPSR1 | |
| SCHEMBL2800311 | 0.85 | UBE2M (0.40) | UBE2MDCUN1D1LMNAALDH1A1TP53 | |
| SCHEMBL2796969 | 0.85 | KCNH2 (0.39) | UBE2MDCUN1D1LMNATP53THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8329694-B2 | Quinoxalinones as antibacterial composition | TOYAMA CHEMICAL CO., LTD. (JP) | 2012-12-11 | — | — | US | disclosed |
| US-20100168418-A1 | NOVEL NITROGENATED HETEROCYCLIC COMPOUND AND SALT THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 2010-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100168418-A1 | NOVEL NITROGENATED HETEROCYCLIC COMPOUND AND SALT THEREOF | ROS1, NOX1, ARG1 | HTR3E 4770/4885HTR3B 4165/4885HTR3A 4231/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.