Biphenyl

Biphenyl

SCHEMBL27964280

CC=CC=CC.[Pt].c1ccc(-c2ccccc2)cc1

nearest known ligand 0.53

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.53
SLC22A2 O15244 1/20 0.42
SLC22A1 O15245 1/20 0.42
SLC22A3 O75751 1/20 0.42
SLC6A4 P31645 1/20 0.42
TAAR1 Q96RJ0 3/20 0.39
CYP1A2 P05177 2/20 0.39
MAPK1 P28482 2/20 0.39
CYP3A4 P08684 1/20 0.39
HSD17B10 Q99714 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
NOTUM Q6P988 1/20 0.39
MMP3 P08254 1/20 0.39
BCL2L1 Q07817 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.37
CYP1A1 P04798 1/20 0.37
CYP1B1 Q16678 1/20 0.37
MAPT P10636 1/20 0.37
ATM Q13315 1/20 0.36
NPC1 O15118 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL28799578 0.84 ALDH1A1 (0.64) ALDH1A1SLC22A2SLC22A1SLC22A3SLC6A4
SCHEMBL29624513 0.81 MAOB (0.54) ALDH1A1MAPK1CYP3A4NPC1RAB9A
Biphenyl SCHEMBL27964564 0.78 ALDH1A1 (0.47) ALDH1A1SLC22A2SLC22A1SLC22A3SLC6A4
SCHEMBL28054656 0.78 ALDH1A1 (0.41) ALDH1A1SLC22A2SLC22A1SLC22A3SLC6A4
Biphenyl SCHEMBL597188 0.77 ALDH1A1 (0.90) ALDH1A1SLC22A2SLC22A1SLC22A3SLC6A4
Biphenyl SCHEMBL28758624 0.77 ALDH1A1 (0.90) ALDH1A1SLC22A2SLC22A1SLC22A3SLC6A4
Biphenyl SCHEMBL2948084 0.75 ALDH1A1 (0.60) ALDH1A1SLC22A2SLC22A1SLC22A3SLC6A4
Biphenyl SCHEMBL664141 0.75 ALDH1A1 (0.60) ALDH1A1SLC22A2SLC22A1SLC22A3SLC6A4
Biphenyl SCHEMBL653702 0.73 ALDH1A1 (0.82) ALDH1A1SLC22A2SLC22A1SLC22A3SLC6A4
Biphenyl SCHEMBL7411979 0.73 ALDH1A1 (0.82) ALDH1A1SLC22A2SLC22A1SLC22A3SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102015845-B Process for the continuous manufacturing of shaped articles and use of silicone rubber compositions in that process MOMENTIVE PERFORMANCE MAT INC 2014-08-06 CN disclosed