Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2657529 | 0.85 | MAOB (0.46) | ALDH1A1L3MBTL1MAPK1TDP1LMNA | |
| SCHEMBL7519973 | 0.85 | MAOB (0.46) | ALDH1A1L3MBTL1MAPK1TDP1LMNA | |
| SCHEMBL3654206 | 0.85 | MAOB (0.46) | ALDH1A1L3MBTL1MAPK1TDP1LMNA | |
| SCHEMBL27372971 | 0.83 | MAOB (0.43) | ALDH1A1L3MBTL1MAPK1TDP1LMNA | |
| SCHEMBL29624513 | 0.80 | MAOB (0.54) | ALDH1A1TP53CA1MGLLCYP3A4 | |
| SCHEMBL29624581 | 0.78 | MAOB (0.52) | ALDH1A1TP53CA1MGLLCYP3A4 | |
| Biphenyl SCHEMBL27964280 | 0.78 | ALDH1A1 (0.53) | ALDH1A1CA1MGLLCYP1A2CYP3A4 | |
| SCHEMBL15573060 | 0.76 | CA1 (0.54) | ALDH1A1TP53CA1MGLLCYP1A2 | |
| SCHEMBL9132430 | 0.76 | CA1 (0.54) | ALDH1A1TP53CA1MGLLCYP1A2 | |
| SCHEMBL724748 | 0.75 | ALDH1A1 (0.50) | ALDH1A1TP53CA1MGLLCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105308023-A | substituted biaryl compounds | UBE INDUSTRIES | 2016-02-03 | — | — | CN | claimed |
| CN-105308023-A | substituted biaryl compounds | UBE INDUSTRIES | 2016-02-03 | — | — | CN | disclosed |