SCHEMBL27964446

SCHEMBL27964446

CCCC(=O)OSCCCF

nearest known ligand 0.41

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.41
CES2 O00748 1/20 0.31
CES1 P23141 1/20 0.31
DGKA P23743 1/20 0.31
CYP1A2 P05177 1/20 0.31
FFAR3 O14843 1/20 0.30
HDAC3 O15379 1/20 0.30
HDAC1 Q13547 1/20 0.30
HDAC2 Q92769 1/20 0.30
HDAC8 Q9BY41 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27857741 0.91 DGKA (0.37) ALDH1A1CES2CES1DGKACYP1A2
SCHEMBL27857783 0.89 DGKA (0.44) ALDH1A1CES2CES1DGKA
SCHEMBL27857681 0.84 NAAA (0.32) ALDH1A1
SCHEMBL27857742 0.80 CA1 (0.35)
SCHEMBL22915377 0.78 DGKA (0.42) ALDH1A1CES2CES1DGKA
SCHEMBL27316330 0.76 DGKA (0.45) ALDH1A1CES2CES1DGKA
SCHEMBL28937523 0.76 DGKA (0.45) ALDH1A1CES2CES1DGKA
SCHEMBL27427969 0.76 DGKA (0.45) ALDH1A1CES2CES1DGKA
SCHEMBL27857733 0.76 MMP1 (0.35) ALDH1A1
SCHEMBL7785942 0.75 CES1 (0.44) ALDH1A1CES2CES1DGKA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102471252-B Process for producing (fluoroalkylthio) acetic acid ester SUMITOMO CHEMICAL CO 2014-07-02 CN disclosed
CN-103709079-A Process for preparation of (fluoroalkylthio)acetic acid esters MASAJI HIROTA HIROYUKI MIYAZAKI TADAYOSHI ITOH 2014-04-09 CN disclosed