Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 2/20 | 0.52 |
| ▸ | F9 | P00740 | 1/20 | 0.51 |
| ▸ | JAK3 | P52333 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 3/20 | 0.48 |
| ▸ | MGLL | Q99685 | 2/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.47 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | IGF1R | P08069 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27964937 | 0.91 | CFD (0.63) | CFDJAK3MGLLENPP2MEN1 | |
| SCHEMBL27965258 | 0.89 | JAK3 (0.50) | JAK3CNR1MGLLENPP2CYP17A1 | |
| SCHEMBL27965272 | 0.87 | JAK3 (0.49) | JAK3CNR1MGLLENPP2CYP17A1 | |
| SCHEMBL27965260 | 0.86 | MGLL (0.64) | JAK3CNR1MGLLENPP2HDAC1 | |
| SCHEMBL27964915 | 0.85 | MGLL (0.66) | JAK3CNR1MGLLHDAC1MEN1 | |
| SCHEMBL27965266 | 0.84 | CNR1 (0.68) | JAK3CNR1MGLLCNR2 | |
| SCHEMBL27964948 | 0.82 | CNR1 (0.62) | JAK3CNR1MGLLMEN1ALDH1A1 | |
| SCHEMBL27965265 | 0.82 | JAK3 (0.52) | JAK3CNR1MGLLMEN1ALDH1A1 | |
| SCHEMBL27734848 | 0.82 | CFD (0.61) | CFDCNR1MGLLTAAR1ENPP2 | |
| SCHEMBL28047630 | 0.82 | CFD (0.57) | CFDCNR1MGLLTAAR1ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103864750-A | Derivative of N-biphenyl dichloroacetamide as well as preparation method and applications thereof | UNIV TSINGHUA | 2014-06-18 | — | — | CN | disclosed |