Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 1/20 | 0.57 |
| ▸ | MGLL | Q99685 | 3/20 | 0.53 |
| ▸ | KIF11 | P52732 | 1/20 | 0.52 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.52 |
| ▸ | ITGAV | P06756 | 2/20 | 0.52 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.51 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.51 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.49 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.48 |
| ▸ | IGF1R | P08069 | 1/20 | 0.47 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28047623 | 0.89 | MGLL (0.51) | CFDMGLLKIF11ITGB3ITGAV | |
| SCHEMBL27734848 | 0.87 | CFD (0.61) | CFDMGLLCYP17A1CYP11B1CYP11B2 | |
| SCHEMBL4082541 | 0.84 | MGLL (0.72) | MGLLKIF11HDAC1CNR1 | |
| SCHEMBL30164935 | 0.84 | MGLL (0.72) | MGLLKIF11HDAC1CNR1 | |
| SCHEMBL2557430 | 0.83 | CFD (0.55) | CFDENPP2 | |
| SCHEMBL13749770 | 0.82 | KIF11 (0.69) | MGLLKIF11ITGB3ITGAVCNR1 | |
| SCHEMBL8064236 | 0.82 | FGFR3 (0.64) | MGLLKIF11CNR1FGFR3KDR | |
| SCHEMBL4091879 | 0.82 | CNR1 (0.71) | MGLLKIF11CNR1 | |
| SCHEMBL27965263 | 0.82 | CFD (0.52) | CFDMGLLCYP17A1CYP11B1CYP11B2 | |
| SCHEMBL28047621 | 0.79 | CFD (0.52) | CFDMGLLKIF11ITGB3ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105111151-B | Aminopyridine derivative as PPAR- gamma modulators | 成都理工大学 | 2018-09-28 | — | — | CN | disclosed |
| CN-105111151-A | Aminopyrimidine derivative used as PPAR-gamma regulator | UNIV CHENGDU TECHNOLOGY | 2015-12-02 | — | — | CN | disclosed |