Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 3/20 | 0.36 |
| ▸ | PDE4A | P27815 | 10/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2559258 | 0.84 | ALDH1A1 (0.53) | ALDH1A1TSHRHTTGAASMN1; SMN2 | |
| SCHEMBL2791777 | 0.81 | POLB (0.39) | PDE4AALDH1A1TSHRPDE4DPDE4B | |
| SCHEMBL1302147 | 0.76 | TTR (0.49) | DRD1ALDH1A1HTTGAASMN1; SMN2 | |
| SCHEMBL140841 | 0.74 | DRD1 (0.53) | DRD1PDE4AALDH1A1TSHRPDE4D | |
| SCHEMBL29440132 | 0.74 | DRD1 (0.53) | DRD1PDE4AALDH1A1TSHRPDE4D | |
| SCHEMBL26699637 | 0.73 | DRD1 (0.49) | DRD1ALDH1A1TSHRHTTPDE4B | |
| SCHEMBL3466337 | 0.73 | DRD1 (0.49) | DRD1ALDH1A1TSHRHTTPDE4B | |
| SCHEMBL29654951 | 0.73 | DRD1 (0.49) | DRD1ALDH1A1TSHRHTTPDE4B | |
| SCHEMBL4135186 | 0.70 | TTR (0.61) | DRD1PDE4AALDH1A1TSHRPDE4D | |
| SCHEMBL140472 | 0.69 | ALDH1A1 (0.70) | DRD1ALDH1A1TSHRHTTPDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8524905-B2 | Processes for preparing 6-(difluoromethoxy)[1]benzofuro[3,2-c]pyridine-9-carbaldehyde, a novel intermediate for the synthesis of PDE IV inhibitors | GLENMARK PHARMACEUTICALS S.A. (CH) | 2013-09-03 | — | — | US | disclosed |
| US-20100168151-A1 | NOVEL PROCESSES FOR PREPARING 6-(DIFLUOROMETHOXY)[1]BENZOFURO[3,2-C]PYRIDINE-9-CARBALDEHYDE, A NOVEL INTERMEDIATE FOR THE SYNTHESIS OF PDE IV INHIBITORS | GLENMARK PHARMACEUTICALS, S.A. (CH) | 2010-07-01 | — | — | US | disclosed |
| WO-2008142542-A2 | PROCESSES FOR PREPARING BENZOFURO [3, 2-C] PYRIDINE- 9-CARBALDEHYDE DERIVATIVES AS NOVEL INTERMEDIATES FOR THE SYNTHESIS OF PDE IV INHIBITORS | GLENMARK PHARMACEUTICALS, S.A. (US) | 2008-11-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100168151-A1 | NOVEL PROCESSES FOR PREPARING 6-(DIFLUOROMETHOXY)[1]BENZOFURO[3,2-C]PYRIDINE-9-CARBALDEHYDE, A NOVEL INTERMEDIATE FOR THE SYNTHESIS OF PDE IV INHIBITORS | PDE4B, PDE4A, PDE4C | DRD1 1984/4885PDE4A 2/4885ALDH1A1 341/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.