Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.46 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2244840 | 0.84 | KMT2A (0.57) | ALDH1A1PDK1KMT2ALMNAKDM4E | |
| SCHEMBL531627 | 0.83 | ALDH1A1 (0.46) | ALDH1A1KMT2AHTTLMNACYP2C19 | |
| SCHEMBL10802204 | 0.77 | ALDH1A1 (0.43) | ALDH1A1PDK1KMT2AHTTTDP1 | |
| SCHEMBL16958967 | 0.75 | PDK1 (0.57) | ALDH1A1PDK1KMT2AXDHLMNA | |
| SCHEMBL10808810 | 0.74 | BCL9 (0.50) | ALDH1A1PDK1KMT2ALMNAKDM4E | |
| SCHEMBL6708261 | 0.74 | MEN1 (0.47) | ALDH1A1KMT2AHTTLMNAKDM4E | |
| SCHEMBL707380 | 0.73 | SMN1; SMN2 (0.48) | ALDH1A1KMT2AKDM4EMEN1SMN1; SMN2 | |
| SCHEMBL317535 | 0.73 | ALDH1A1 (0.56) | ALDH1A1KMT2AHTTLMNAKDM4E | |
| SCHEMBL10788442 | 0.73 | TTR (0.49) | ALDH1A1PDK1KMT2AXDHTDP1 | |
| SCHEMBL3911316 | 0.72 | TTR (0.44) | ALDH1A1PDK1KMT2ALMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101952280-B | Bicyclic heterocyclic derivative | DAINIPPON SUMITOMO PHARMA CO | 2014-04-23 | — | — | CN | disclosed |